epiid	pmid	organismid	tissue	diagnosis	familycontrol	platform	method	description	disease	epigenome	class
1	12908672	9606	Blood		Case-control based	RT-PCR	RT-PCR	Although the epigenetic analysis was conducted for only several hundred base pairs of DRD2,the fact that numerous studies identified nonuniform methylation patterns across the clones of bisulfite-modified DNA from the same individual, as well as nonuniform patterns across different individuals,argues for the universality of intra- and interindividual epigenetic variation. 	Schizophrenia	DNA methylation	Epigenome
2	15930386	9606	Brain		Case-control based	Bisulfite sequencing//qRT-PCR	Bisulfite sequencing//qRT-PCR	We also found that DNA methylation status of SOX10 also was associated with other oligodendrocyte gene expressions in schizophrenia. This may be specific to SOX10, because the CpG island of OLIG2, which encodes another oligodendrocyte-specific transcription factor, was rarely methylated in brains, and the methylation status of myelin-associated oligodendrocytic basic protein, which encodes structural protein in oligodendrocytes, did not account for their expressions or other oligodendrocyte gene expressions. Therefore, DNA methylation status of the SOX10 CpG island could be an epigenetic sign of oligodendrocyte dysfunction in schizophrenia.	Schizophrenia	DNA methylation	Epigenome
3	16984965	9606	Brain		Case-control based	RT-PCR	RT-PCR	These findings suggest that MB-COMT over-expression due to promoter hypomethylation and/or hyperactive allele of COMT may increase dopamine degradation in the frontal lobe providing a molecular basis for the shared symptoms of schizophrenia and bipolar disorder.	Schizophrenia	DNA methylation	Epigenome
4	16984965	9606	Brain		Case-control based	RT-PCR	RT-PCR	Furthermore, we found a correlation between COMT Val homozygosity and DNA hyper-methylation of the RELN promoter in a cAMP-response element as determined using a previously described method.	Schizophrenia	DNA methylation	Epigenome
5	17942719	9606	Brain		Case-control based		RT-PCR//Western Blotting	In addition, in female schizophrenia postmortem brain samples lower H3K4 methylation levels at the GAD67 promoter with resultant decreased gene expression has been described.	Schizophrenia	Histone modification	Epigenome
6	18172431	9606	Blood	DSM-IV	Case-control based			We found significantly lower levels of ANP mRNA in patients with eating disorders. 	Anorexia Nervosa	DNA methylation	Epigenome
7	19046818	9606	Blood	DSM-IV	Case-control based			We found significantly higher levels of CB1 receptor mRNA in the blood of patients with AN(DCT: 3.9(1.0); KW: 11.31; P=0.003) and BN(DCT:  3.7(1.7)) when compared to controls(DCT:  4.6(0.6); Dunn芒鈧劉s test AN vs. Controls: P<0.05; BN vs. Controls: P<0.001) measured by quantitative real-time PCR. 	Anorexia Nervosa	DNA methylation	Epigenome
8	19728374	9606	Blood	DSM-IV	Case-control based			Patients showed an elevated expression of DAT mRNA when compared with the controls and a downregulation of the DRD2 expression. 	Anorexia Nervosa	DNA methylation	Epigenome
9	19728374	9606	Blood	DSM-IV	Case-control based			The upregulation of the DAT gene was accompanied by a hypermethylation of the gene芒鈧劉s promoter in the AN and BN group while a significant hypermethylation of the DRD2 promoter was only present in the AN group. 	Anorexia Nervosa	DNA methylation	Epigenome
10	19759294	9606	Brain	DSM-IV	Case-control based	Western blotting	Western blotting	These changes in H3 acetylation and HDAC2 expression mediate long-lasting positive neuronal adaptations, since infusion of HDAC inhibitors into the nucleus accumbens, which increases histone acetylation, exerts robust antidepressant-like effects in the social defeat paradigm and other behavioral assays. 	Major Depressive Disorder	Histone modification	Epigenome
11	20009564	10090	Brain	Others	Case-control based	MeDIP	MeDIP	In the current study, we used an established whole-embryo culture system with strictly controlled staging (timed by somite number) and alcohol dose to investigate the effect of alcohol exposure during early embryo development on genome-wide DNA methylation patterns. Methyl-DNA immunoprecipitation followed by microarrays (MeDIP-chip) was used for DNA methylation mapping and measurement across the mouse embryo genome. The methylation microarray data was validated using Sequenom Mass ARRAY and correlated with gene expression data. Average methylation signals in the entire promoter region were used to characterize mouse embryo DNA methylation profiles. In addition, a novel two-consecutive probe analysis was employed to detect alcohol-induced methylation changes in localized genomic regions (the same direction change of two probes stretched over 150 nucleotides). Based on our integrated analysis, we conclude that alcohol exposure during early neurulation induces significant changes in DNA methylation patterns and gene expression that may contribute to FASD development.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
12	20009564	10090	Brain	Others	Case-control based	MeDIP//Sequenom	MeDIP//Sequenom	In the current study, we used an established whole-embryo culture system with strictly controlled staging (timed by somite number) and alcohol dose to investigate the effect of alcohol exposure during early embryo development on genome-wide DNA methylation patterns. Methyl-DNA immunoprecipitation followed by microarrays (MeDIP-chip) was used for DNA methylation mapping and measurement across the mouse embryo genome. The methylation microarray data was validated using Sequenom Mass ARRAY and correlated with gene expression data. Average methylation signals in the entire promoter region were used to characterize mouse embryo DNA methylation profiles. In addition, a novel two-consecutive probe analysis was employed to detect alcohol-induced methylation changes in localized genomic regions (the same direction change of two probes stretched over 150 nucleotides). Based on our integrated analysis, we conclude that alcohol exposure during early neurulation induces significant changes in DNA methylation patterns and gene expression that may contribute to FASD development.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
13	20176366	9606	Blood	DSM-IV	Case-control based			Methylation of single CpG residues in the E2F binding site was inversely related to POMC expression. Our preliminary data on pattern of POMC regulation suggests an association with the underweight state rather than with persisting trait markers of AN. In contrast to POMC expression in the central nervous system, peripheral POMC mRNA expression decreased with malnutrition and hypoleptinemia. 	Anorexia Nervosa	DNA methylation	Epigenome
14	20176366	9606	Blood	DSM-IV	Case-control based	Bisulfite pyrosequencing	Bisulfite sequencing	Our preliminary data on pattern of POMC regulation suggests an association with the underweight state rather than with persisting trait markers of AN.	Anorexia Nervosa	DNA methylation	Epigenome
15	20439746	9606	Blood	DSM-IV	Case-control based	Illumina 27K array	27K array	In this context, it is noteworthy that a gene encoding one of these enzymes(DNMT3B) is both uniquely unmethylated and shows significantly less methylation(P<0.017) in the PTSD-affected group; and that another, closely related gene(DNMT3L) is significantly more methylated(P=0.037) among individuals with vs. without PTSD. 	Posttraumatic Stress Disorder	DNA methylation	Epigenome
16	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G57/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
17	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G60/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
18	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G63/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
19	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G66/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
20	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G69/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
21	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G4/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
22	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G7/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
23	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G8/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
24	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G27/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
25	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G19/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
26	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G32/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
27	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G72/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
28	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G30/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
29	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G17/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
30	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G75/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
31	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G88/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
32	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G25/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
33	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G78/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
34	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G91/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
35	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G81/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
36	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G94/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
37	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G84/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
38	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G97/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
39	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G48/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
40	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G51/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
41	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G53/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
42	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G55/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
43	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G58/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
44	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G61/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
45	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G64/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
46	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G67/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
47	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G33/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
48	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G5/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
49	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G21/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
50	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G70/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
51	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G26/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
52	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G2/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
53	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G6/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
54	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G37/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
55	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G11/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
56	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G22/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
57	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G38/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
58	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G39/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
59	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G40/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
60	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G15/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
61	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G14/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
62	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G9/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
63	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G73/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
64	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G85/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
65	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G98/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
66	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G49/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
67	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G52/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
68	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G43/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
69	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G79/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
70	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G92/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
71	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G82/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
72	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G95/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
73	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G76/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
74	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G89/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
75	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G54/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
76	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G10/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
77	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G56/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
78	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G47/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
79	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G59/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
80	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G62/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
81	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G3/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
82	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G65/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
83	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G68/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
84	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G71/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
85	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G34/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
86	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G31/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
87	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G74/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
88	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G87/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
89	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G44/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
90	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G16/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
91	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G12/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
92	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G35/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
93	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G77/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
94	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G90/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
95	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G13/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
96	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G18/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
97	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G41/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
98	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G83/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
99	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G96/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
100	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G86/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
101	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G99/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
102	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G42/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
103	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G36/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
104	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G46/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
105	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G29/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
106	20626555	10090	Brain	Others	Case-control based	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Sequenom MassARRAY//MeDIP//Cell Cycle Kinetics//Immunocytochemical Analysis	Thus, ethanol disrupts growth factor-related cell cycle progression by inducing checkpoint restriction at the G1/S transition through a feed-forward system involving the methylation of G20/M regulators.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
107	20649982	9606	Blood//Brain	DSM-IV	Case-control based	Bisulfite sequencing//qRT-PCR	Bisulfite sequencing//qRT-PCR	In patients, we detected higher degree of methylation in the left parahippocampus gyrus than in the right one.	Schizophrenia	DNA methylation	Epigenome
108	21223309	9606	Brain	Others	Case-control based	MeDIP//qPCR//Immunocytochemistry//Immunostaining Intensity Analysis//Cell Migration Assay	MeDIP//qPCR//Immunocytochemistry//Immunostaining Intensity Analysis//Cell Migration Assay	The data indicate that alcohol prevents normal DNA methylation programming of key neural stem cell genes and retards NSC differentiation.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
109	21296890	9606	Brain	Others	Case-control based	EpiQuik Nuclear Extraction Kit//Western Blotting//Methylation-specific PCR//Immunohistochemical Detection//Co-immunoprecipitation	EpiQuik Nuclear Extraction Kit//Western Blotting//Methylation-specific PCR//Immunohistochemical Detection//Co-immunoprecipitation	Furthermore, sequestration of Dnmt1 in the cytoplasm results in global DNA hypomethylation in human and mouse brains	Neurocognitive Disorder With Lewy Bodies	DNA methylation	Epigenome
110	21350482	9606	Blood	DSM-IV	Case-control based	Illumina 27K array	27K array	Methylation of ADCYAP1R1 is also associated with PTSD(p<0.001)	Posttraumatic Stress Disorder	DNA methylation	Epigenome
111	21453976	9606	Blood	DSM-IV	Case-control based	HRM	HRM	We observed increased DNA methylation in the promoter region of the 5HTR1A gene of SCZ and BPD. This could explain the reported decrease of the receptor expression. The current study supports the growing interest of DNA methylation in psychopathology.	Schizophrenia	DNA methylation	Epigenome
112	21550210	9606	Brain		Case-control based	Bisulfite sequencing//qRT-PCR	Bisulfite sequencing//qRT-PCR	Interestingly, promoter DNA of HTR2A was hypermethylated at and around the -1438A/G polymorphic site, but was hypomethylated at and around T102C polymorphic site in SCZ and BD compared to the controls. Furthermore, epigenetic down-regulation of HTR2A was associated with early age of disease onset in SCZ and BD.	Schizophrenia	DNA methylation	Epigenome
113	21714072	9606	Blood	DSM-IV	Case-control based	Illumina 27K array	27K array	TABLE I Evaluation of CpG Sites in Differentially Methylated Genes From the Literature	Posttraumatic Stress Disorder	DNA methylation	Epigenome
114	21908516	9606	Blood	DSM-IV	Case-control based	Illumina 27K array	27K array	Supplementary Table 3 The top 100 differentially methylated CpG sites in MZ twins discordant for SZ(n=11 MZ pairs, 22 individuals). Loci are ranked by mean 脦鈥澝幝	Schizophrenia	DNA methylation	Epigenome
115	21908516	9606	Blood	DSM-IV	Case-control based	Illumina 27K array	27K array	Supplementary Table 4 The top 100 differentially methylated CpG sites in MZ twins discordant for BD(n=11 MZ pairs, 44 individuals). Loci are ranked by mean 脦鈥澝幝	Bipolar Disorder	DNA methylation	Epigenome
116	22065254	9606	Brain		Case-control based	ChIP-seq	ChIP-seq	Subjects with autism showed no evidence for generalized disruption of the developmentally regulated remodeling of the H3K4me3 landscape that defines normal prefrontal cortex neurons in early infancy. However, excess spreading of H3K4me3 from the transcription start sites into downstream gene bodies and upstream promoters was observed specifically in neuronal chromatin from 4 of 16 autism cases but not in controls.	Autism Spectrum Disorder	Histone modification	Epigenome
117	22077067	9606	Blood		Case-control based	Illumina 450K array	450K array	However, log FOXP3 DNA methylation patterns, log MRP 8/14 levels, and log hsCRP levels showed significant group differences(Table 2).	Obstructive Sleep Apnea Hypopnea	DNA methylation	Epigenome
118	22139575	9606	Blood	DSM-IV	Case-control based	Bisulfite pyrosequencing	Bisulfite sequencing	Aberrant methylation was not detectable using bisulfte restriction analysis, but a signifcantly increased methylation of HTR2A, NR3C1, MAOA, MAOB and soluble COMT(S-COMT) was revealed for BPD patients using pyrosequencing. For HTR2A the average methylation of four CpG sites was 0.8% higher in BPD patients compared with controls(p=0.002). The average methylation of NR3C1 was 1.8% increased in BPD patients compared with controls(p=0.0003) and was higher at 2 out of 8 CpGs(p 芒鈥奥	Borderline Personality Disorder	DNA methylation	Epigenome
119	22198720	9606	Blood	DSM-IV	Case-control based	BSP-seq	Bisulfite sequencing	The results showed that there was no significant difference in overall DNA methylation ratios between patients and controls either in the female group(P=0.42) or in the male group(P=0.24). Of 15 CpG residues that showed significant differences in DNA methylation status between the patient group and the control group in females, eight of which had an increased level and seven, a decreased level, with a combined P value of 1(df=160). In male subjects, however, six individual CpG residues showed an increased methylation level with a combined P value of 5.80E-35(df=158). In conclusion, abnormalities of DNA methylation at the MAOA promoter may be associated with schizophrenia in males.	Schizophrenia	DNA methylation	Epigenome
120	22302827	9606	Brain		Family based	Illumina microarray	Microarray	Three out of six genes(GIPC1, BCL2L1 and UBE1) showed significantly increased levels of H3K4 tri-methylation in alcoholics(Figure 6B), which was consistent with the up-regulation of their transcripts, while H3K4me3 levels of the other three genes did not differ between the groups. 	Alcohol Use Disorder	Histone modification	Epigenome
121	22302827	9606	Brain		Family based	Illumina microarray	Microarray	We used a qPCR-based method to measure DNA methylation in frontal cortex of alcoholic and control cases for three ERV families and observed a reduction of DNA methylation in the LTR region of these retrotransposons(Figure 6A), suggesting that activation of ERVs in alcoholics was due, at least in part, to DNA hypomethylation. 	Alcohol Use Disorder	DNA methylation	Epigenome
122	22391769	9606	Blood	DSM-IV	Case-control based		Bisulfite sequencing	The results of this study suggest COMT promoter region methylation is largely influenced by COMT genotype and that physical activity plays a significant role in epigenetic modulation of COMT.	Schizophrenia	DNA methylation	Epigenome
123	22398003	9606	Blood	DSM-IV	Case-control based	Bisulfite pyrosequencing	Bisulfite sequencing	POMC promoter-specific DNA methylation was not affected by diagnosis or nutritional status but significantly negatively associated with cigarette smoking.	Anorexia Nervosa	DNA methylation	Epigenome
124	22426120	9606	Blood	DSM-IV	Case-control based		Pyrosequencing//RT-PCR	Global methylation results revealed a highly significant hypomethylation in patients with schizophrenia(P<2.0脙鈥	Schizophrenia	DNA methylation	Epigenome
125	22571925	9606	Brain	DSM-IV	Case-control based	ChIP-Seq	ChIP-Seq	In the present study we have quantified the expression of transcript variants of the three synapsin genes and investigated their relationship to H3K4me3 promoter enrichment in post-mortem brain samples. We found that histone modification marks were significantly increased in bipolar disorder and major depression and this effect was correlated with significant increases in gene expression. 	Bipolar Disorder	Histone modification	Epigenome
126	22571925	9606	Brain	DSM-IV	Case-control based	ChIP-Seq	ChIP-Seq	In the present study we have quantified the expression of transcript variants of the three synapsin genes and investigated their relationship to H3K4me3 promoter enrichment in post-mortem brain samples. We found that histone modification marks were significantly increased in bipolar disorder and major depression and this effect was correlated with significant increases in gene expression. 	Major Depressive Disorder	Histone modification	Epigenome
127	22571925	9606	Brain	DSM-IV	Case-control based	ChIP-seq//qRT-PCR	ChIP-seq//qRT-PCR	We found that histone modification marks were significantly increased in bipolar disorder and major depression and this effect was correlated with significant increases in gene expression. 	Bipolar Disorder	Histone modification	Epigenome
128	22571925	9606	Brain	DSM-IV	Case-control based	ChIP-seq//qRT-PCR	ChIP-seq//qRT-PCR	We found that histone modification marks were significantly increased in bipolar disorder and major depression and this effect was correlated with significant increases in gene expression. 	Major Depressive Disorder	Histone modification	Epigenome
129	22914673	9606	Blood	DSM-IV-TR	Case-control based	Sequenom EpiTYPER platform	MassARRAY	Results suggest that MAOA promoter hypermethylation is associated with ASPD and may contribute to downregulation of MAOA gene expression, as indicated by functional assays in vitro, and regression analysis with whole-blood serotonin levels in offenders with ASPD.	Antisocial Personality Disorder	DNA methylation	Epigenome
130	22924764	9606	Brain	DSM-IV	Case-control based	Illumina GoldenGate Methylation Profiling Panel//Illumina GoldenGate Methylation Array Assay//Sequenom MassARRAY EpiTYPER	Illumina GoldenGate Methylation Profiling Panel//Illumina GoldenGate Methylation Array Assay//Sequenom MassARRAY EpiTYPER	Table2 DNA Methylation Differences between Cases with Alcohol Dependence and Controls	Alcohol Use Disorder	DNA methylation	Epigenome
131	22961555	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Supplementary TableS2: Top 100-ranking differentially methylated CpG sites	Schizophrenia	DNA methylation	Epigenome
132	23182420	9606	Blood	DSM-IV-R	Case-control based	Bisulfite pyrosequencing	Bisulfite sequencing	Table 1 Details of the primers used in methylation analysis and the number included in analysis after quality control. For SERT, BDNF exon IV, BDNF exon VI and DRD2, the cycling conditions in the bisulfite 芒鈧€	Anorexia Nervosa	DNA methylation	Epigenome
133	23182420	9606	Blood	DSM-IV	Case-control based			DNA methylation levels in the promoter regions were not significantly different between the two groups for any of the genes examined.	Anorexia Nervosa	DNA methylation	Epigenome
134	23328840	9606	Blood		Case-control based	Bisulfite pyrosequencing	Bisulfite sequencing	However, a CpG site located at position -171(relative to transcription start site), approximating important transcriptional elements, displayed significantly higher methylation levels in the OSAab group as compared with the OSAn or control groups(81.5%脗卤3.5%, 74.8%脗卤1.4%, and 74.5%脗卤1.7%, respectively; P<.001). eNOS mRNA expression levels were assessed in a separate group of children and were significantly reduced in the OSAab group in comparison with the OSAn group.	Obstructive Sleep Apnea Hypopnea	DNA methylation	Epigenome
135	23387924	9606	Blood	DSM-IV	Case-control based	Illumina 27K array	27K array	Table 2 Top 10 enriched GO category in the differentially hypermethylated genes.	Alcohol Use Disorder	DNA methylation	Epigenome
136	23417893	9606	Blood	DSM-IV	Case-control based			Compared to noneating disordered women, women with BN and comorbid BPD(or BN with a history of suicidality) showed significantly more methylation of specific exon 1C sites. 	Bulimia Nervosa	DNA methylation	Epigenome
137	23417893	9606	Blood	DSM-IV-TR	Case-control based	Sequenom EpiTYPER platform	MassARRAY	TABLE 2. Localizing information for specific exon 1C CpGs retained for statistical analyses	Borderline Personality Disorder	DNA methylation	Epigenome
138	23423139	9606	Blood	DSM-IV	Case-control based	Sequenom MassARRAY EpiTYPER	MassARRAY	There was a significant reduction in levels of methylation in four of these sites in people with Sz(Table 2) with further analyses revealing a significant reduction in levels of DNA methylation in three sites in people with Def-Sz and Non-Def-Sz(Table 3), plus an addition site in the Non-Def-Sz. Examining the pooled methylation data showed that there was a significant decrease in methylation associated with the diagnoses of Sz but not with other factors such as suicide, gender, age, tissue pH or PMI(Table 4). In addition, there were very similar reductions in DNA methylation in all CpG sites in tissue from both Def-Sz and Non-Def-Sz compared with controls, which meant there was no difference in DNA methylation between the two forms of Sz.	Schizophrenia	DNA methylation	Epigenome
139	23580197	10090	Brain	Others	Case-control based	MeDIP//qPCR	MeDIP//qPCR	We found long-lasting alterations in DNA methylation as a result of fetal alcohol exposure, specifically in the imprinted regions of the genome harboring ncRNAs and sequences interacting with regulatory proteins.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
140	23815974	9606	Blood//Brain		Case-control based		Western Blotting//RT-PCR	A diagnosis of schizophrenia is a significant predictor for increased GLP, SETDB1 mRNA expression and H3K9me2 levels in both postmortem brain and lymphocyte samples. G9a mRNA is significantly increased in the UIC lymphocyte samples as well. Increased HMT mRNA expression is associated with worsening of specific symptoms, longer durations of illness and a family history of schizophrenia.	Schizophrenia	Histone modification	Epigenome
141	23999529	9606	Brain	DSM-IV	Case-control based	Illumina 450K array	450K array	Table 1 Genome-wide significant DMRs associated with ASD	Autism Spectrum Disorder	DNA methylation	Epigenome
142	24115305	9606	Buccal swabs		Case-control based	Sequenom EpiTYPER platform	MassARRAY	No evidence for altered global or gene-specific DNA methylation was observed in association with AN.	Anorexia Nervosa	DNA methylation	Epigenome
143	24312678	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	While significant correlations between methylation levels at some CpG sites and physiological measures were identified, overall the variation in DNA methylation between patients was small, and the significance of this variation remains equivocal. 	Panic Disorder	DNA methylation	Epigenome
144	24367640	9606	Blood		Case-control based	Illumina 27K array	27K array	Table 2 Differentially methylated CpGs by 27K bead chip and pyrosequencing.	Borderline Personality Disorder	DNA methylation	Epigenome
145	24402055	9606	Blood		Case-control based	SOLiD platform	ABI Solid Sequencing	Our MWAS suggested a considerable number of effects, with 25 sites passing the highly conservative Bonferroni correction and 139 sites significant at a false discovery rate of 0.01. 	Schizophrenia	DNA methylation	Epigenome
146	24523928	9606	Blood		Case-control based	Illumina 450K array	450K array	We identified four highly-methylated CpG sites(CpG 34, CpG 35, CpG 46, and CpG 47) in the MT2 region that are known to regulate expression of the OXTR gene in patients with AN. Methylation level was inversely related to BMI.	Anorexia Nervosa	DNA methylation	Epigenome
147	24523928	9606	Buccal Swabs	DSM-IV	Case-control based			Epigenetic misregulation of the OXTR gene may be implicated in anorexia nervosa, which may either be a mechanism linking environmental adversity to risk or may be a secondary consequence of the illness.	Anorexia Nervosa	DNA methylation	Epigenome
148	24662927	9606	Brain	DSM-IV	Case-control based	Illumina 450K array	450K array	Table 1 The list of astrocyte associated genes within the dataset	Major Depressive Disorder	DNA methylation	Epigenome
149	24737292	9606	Blood	DSM-IV	Case-control based	MeDIP-seq	MeDIP-seq	Table 2 Differential methylation of genes detected from microchip arrays	Autism Spectrum Disorder	DNA methylation	Epigenome
150	24737292	9606	Blood	DSM-IV	Case-control based	MeDIP-seq	MeDIP-seq	The hypermethylation of ENO2 within the promoter region was confirmed by BSP to be present in 14.5 %(19/131) of the total of the autistic samples. The mean ENO2 RNA level in these 19 autistic samples was reduced by about 70 % relative to that in controls. The average level of ENO2 protein expression in the 19 autistic samples(15.18脗卤3.51 脦录g/l) was about half of that in the controls(33.86脗卤8.16 脦录g/l).	Autism Spectrum Disorder	DNA methylation	Epigenome
151	24751885	9606	Brain	Others	Case-control based	Affymetrix Human Genome U133 Plus 2.0 Array//qRT-PCR	Affymetrix Human Genome U133 Plus 2.0 Array//qRT-PCR	DNA sequence motif analysis of genes epigenetically altered by EtOH identified major motifs representing potential binding sites for transcription factors.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
152	24801751	9606	Blood	DSM-V	Case-control based	Sequenom EpiTYPER platform	MassARRAY	We observed a significant site 脙鈥	Borderline Personality Disorder	DNA methylation	Epigenome
153	24929637	9606	Brain		Case-control based	Illumina 450K array	450K array	Table S3. Top 100 ranked DMPs, ranked on p-value and magnitude of DNA methylation change	Major Depressive Disorder	DNA methylation	Epigenome
154	25041603	9606	Brain//Cell lines(SH-Sy5y)	DSM-IV	Case-control based	Illumina 27K array	27K array	Lower KCNQ3 exon 11 DNA methylation was observed in the Stanley Medical Research Institute replication cohort, although only after correcting for mood stabilizer status. 	Bipolar Disorder	DNA methylation	Epigenome
155	25158004	9606	Blood		Case-control based	MeDIP-seq//Pyrosequencing	MeDIP-seq//Pyrosequencing	MORC1 is thus the first identified epigenetic marker of ELS to be present in blood cell progenitors at birth and in the brain in adulthood.	Major Depressive Disorder	DNA methylation	Epigenome
156	25158004	10116	Brain		Case-control based	MeDIP-seq//Pyrosequencing	MeDIP-seq//Pyrosequencing	MORC1 is thus the first identified epigenetic marker of ELS to be present in blood cell progenitors at birth and in the brain in adulthood.	Major Depressive Disorder	DNA methylation	Epigenome
157	25223586	10116	Brain		Case-control based	MeDIP-seq	MeDIP-seq	There was a significant negative correlation between the Bdnf1 expression and DNA methylation level at the promoter Bdnf p1 in non-deprived rats(R=-0.713, F1,13=12.40, P=0.004). This correlation was lost after SD(R=+0.15, F1,14=0.30, P=0.59; Fig. 2c). We found no correlation for Bdnf p4- or p9-driven transcription. 	Circadian Rhythm Sleep Wake Disorders	DNA methylation	Epigenome
158	25243493	9606	Brain		Case-control based	Illumina 27K array	27K array	Table 2 Correlation between differential gene expression and DNA methylation in discovery and validation datasets	Schizophrenia	DNA methylation	Epigenome
159	25243493	9606	Brain		Case-control based	Illumina 27K array	27K array	Four of the identified CGPs were found to significantly correlate with the differential expression and methylation of the PIK3R1, BTN3A3, NHLH1, and SLC16A7 in psychotic patients(p<0.05, FDR q<0.2)	Bipolar Disorder	DNA methylation	Epigenome
160	25243493	9606	Brain		Case-control based	Illumina 27K array	27K array	Table 3 Summary of correlations between CpGs and genes under methylation regulation in previous studies	Schizophrenia	DNA methylation	Epigenome
161	25290267	9606	Brain	DSM-IV	Case-control based	MeDIP-seq	MeDIP-seq	As shown in Figure 1c, DNMT3A and DNMT3B expression levels were significantly increased in the autism cerebellum relative to control samples, suggesting a compensatory increase in de novo DNA methylation in the autism cerebellum.	Autism Spectrum Disorder	DNA methylation	Epigenome
162	25290267	9606	Brain	DSM-IV	Case-control based	MeDIP-seq	MeDIP-seq	As shown in Figure 1d, the results indicated a significant increase in both TET1 and TET3 expression with no significant difference in TET2 in case compared with control cerebellum.	Autism Spectrum Disorder	DNA methylation	Epigenome
163	25424713	9606	Blood		Case-control based	Illumina 450K array	450K array	In total, 11320 CpGs were differentially methylated in SZ cases versus controls(5% FDR correction). Of these, 1095 CpGs are associated with 1226 transcripts in cis(after locus-specific correction).(Supplementary Table 1: Probe annotation of 11,320 CpGs)	Schizophrenia	DNA methylation	Epigenome
164	25424713	9606	Blood		Case-control based	Illumina 450K array	450K array	We identified one DMDE locus on chromosome 10 with genome-wide significant evidence of association with SZ. SNP rs11191514:C>T(chr10.hg19:c.104773364C>T) at this locus represents an mQTL associated with differential DNA methylation between cases and controls that is correlated with the expression of a gene that is also differentially expressed between cases and controls(Figures 3a芒鈧€渃).	Schizophrenia	DNA methylation	Epigenome
165	25424713	9606	Blood		Case-control based	Illumina 450K array	450K array	In addition to rs11191514:C>T, we identified four additional independent DMDE SNPs associated with SZ with a significance level of P<0.01(Supplementary Table 3), that is, these SNPs are at best suggestive of a susceptibility locus for SZ.	Schizophrenia	DNA methylation	Epigenome
166	25587773	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Supplementary Table S1. 363 differentially methylated CpG sites in the discovery set of samples at FDR 5% correction.	Major Depressive Disorder	DNA methylation	Epigenome
167	25612291	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Table 2. CpG sites with non-zero linear coefficients	Borderline Personality Disorder	DNA methylation	Epigenome
168	25612291	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Table 2: CpG sites with none-zero linear coefficients. 	Major Depressive Disorder	DNA methylation	Epigenome
169	25734057	9606	Blood	DSM-IV-TR	Case-control based	MeDIP-Seq	MeDIP-Seq	Supplementary Table 1:The hypermethylated and hypomethylated promoters in SZs.	Schizophrenia	DNA methylation	Epigenome
170	25734057	9606	Blood	DSM-IV-TR	Case-control based	MeDIP-Seq	MeDIP-Seq	Supplementary Table 3: The hypermethylated and hypomethylated promoters in BPs.	Bipolar Disorder	DNA methylation	Epigenome
171	25878217	9606	Blood		Case-control based	Illumina 450K array	450K array	Table 2. Candidate differentially methylated regions(DMRs) associated with 12-month total AOSI score, an indicator of autism risk	Autism Spectrum Disorder	DNA methylation	Epigenome
172	25918994	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Table 2 Top-ranked differentially methylated probes(DMPs) in six adult MZ twin pairs discordant for depression, and potential neuropsychiatric relevance of their associated genes	Depressive Disorder	DNA methylation	Epigenome
173	25944409	10090	Brain		Case-control based	Illumina 450K array	450K array	A significant decrease in DNA methylation of CNR1 gene promoter was revealed in the prefrontal cortex of addict-like mice, which was associated with an up regulation of CB1 protein expression in the same brain area. The pharmacological blockade(rimonabant 3 mg/kg; i.p.) of CB1 receptor during the late training period reduced the percentage of mice that accomplished addiction criteria, which is in agreement with the reduced performance of CB1 knockout mice in this operant training.	Eating Disorder	DNA methylation	Epigenome
174	26003415	9606	Blood		Case-control based	Illumina 450K array	450K array	Our findings indicate that imprinting disorders are rare but probably under-diagnosed in patients with intellectual disability and moreover point to DNA methylation changes as potential alternative means to identify deregulated genes involved in the pathogenesis of intellectual disability.The most frequently altered imprinted gene region was BLCAP in which a total of 4 cases showed an increase of methylation of between 10% and 12% as compared to the controls. 	Intellectual Disability	DNA methylation	Epigenome
175	26003415	9606	Blood		Case-control based	Illumina 450K array	450K array	Our findings indicate that imprinting disorders are rare but probably under-diagnosed in patients with intellectual disability and moreover point to DNA methylation changes as potential alternative means to identify deregulated genes involved in the pathogenesis of intellectual disability.(Fig. 1. Result of targeted bisulfite pyrosequencing.)	Intellectual Disability	DNA methylation	Epigenome
176	26017091	9606	Blood	Others	Case-control based	PCR//Pyrosequencing	PCR//Pyrosequencing	DNA sequence motif analysis of genes epigenetically altered by EtOH identified major motifs representing potential binding sites for transcription factors.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
177	26017091	9606	Blood		Case-control based	Illumina 450k array	450K array	A higher methylation status of the SLC6A4 promoter was significantly associated with worse clinical presentations(more hyperactive-impulsive symptoms and more commission errors). 	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
178	26056378	9606	Brain		Case-control based	Illumina 450K array	450K array	SM 2.3 List of the 100 most correlated probes 	Schizophrenia	DNA methylation	Epigenome
179	26178076	9606	Brain	Others	Case-control based	Illumina HumanMethylation450 BeadChip//Pyrosequencing	Illumina HumanMethylation450 BeadChip//Pyrosequencing	The changes occur in genes related to protocadherins, glutamatergic synapses, and hippo signaling. The results were found to be similar in another heterogeneous replication group of six FASD children.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
180	26285129	9606	Buccal swabs	DSM-IV	Case-control based	Sequenom MassARRAY	MassARRAY	In multivariate linear regression analyses adjusted for a range of participant characteristics including antidepressant use, depression at baseline, as well as chronic late-life depression over the 12-year follow-up, were associated with overall higher BDNF methylation levels, with two sites showing significant associations(promoter I, 脦鈥	Major Depressive Disorder	DNA methylation	Epigenome
181	26324104	9606	Blood	DSM-IV	Case-control based	Illumina HumanMethylation450 BeadChip Kit//Microarray	450K array//Microarray	145 participants also had neuroimaging data available. Based on previous research, we examined DNA methylation at the CpG locus cg13989295 as well as DNA methylation adjusted for genotype at the methylation-associated SNP(rs7208505) in relationship to whole-brain cortical thickness, posttraumatic stress disorder symptoms(PTSD), and depression symptoms.	Posttraumatic Stress Disorder	DNA methylation	Epigenome
182	26361058	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	sing pre-deployment SKA2 methylation levels and childhood trauma exposure, we found that the previously published suicide prediction rule significantly predicted post-deployment PTSD symptoms(AUC=0.66, 95% CI: 0.53芒鈧€	Posttraumatic Stress Disorder	DNA methylation	Epigenome
183	26503909	9606	Blood	DSM-IV	Case-control based	Illumina Hiseq2000	MBD-seq	Table III Hypermethylation genes shared between paranoid and undifferentiated SCZ samples.	Schizophrenia	DNA methylation	Epigenome
184	26763658	9606	Brain	DSM-IV	Case-control based	Illumina HumanMethylation450 BeadChip assays	Illumina HumanMethylation450 BeadChip assays	Table S3.   Differentially expression genes paired with hypermethylated CpGs	Alcohol Use Disorder	DNA methylation	Epigenome
185	26763658	9606	Brain	DSM-IV	Case-control based	Illumina HumanMethylation450 BeadChip assays	Illumina HumanMethylation450 BeadChip assays	Table S4.   Differentially expression genes paired with hypomethylated CpGs.	Alcohol Use Disorder	DNA methylation	Epigenome
186	26784972	9606	Brain	Others	Case-control based	Pyrosequencing//Whole-genome Bisulfite Sequencing//Illumina Infinium450 Array	Pyrosequencing//Whole-genome Bisulfite Sequencing//Illumina Infinium450 Array	Table S3: Differentially methylated promoters in LBD related to changes in gene expression (log2-fold change)	Neurocognitive Disorder With Lewy Bodies	DNA methylation	Epigenome
187	27045843	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	The present results support previous evidence for MAOA hypomethylation as a PD risk marker and suggest reversibility of MAOA hypomethylation as a potential epigenetic correlate of response to CBT. 	Panic Disorder	DNA methylation	Epigenome
188	27047397	9606	Blood	ICD-10	Case-control based	Illumina Infinium Human Methylation450 BeadChip	450K array	Table 5 Top hit genes from MVP analysis of NEW(N=21)(ESR1, MOG, and BDNF) and OLD(MOG and GABBR1) association with CY-BOCS baseline(A) CY-BOCS BASELINE	Obsessive Compulsive Disorder	DNA methylation	Epigenome
189	27047397	9606	Blood	ICD-10	Case-control based	Illumina Infinium Human Methylation450 BeadChip	450K array	Table 5 Top hit genes from MVP analysis of NEW(N=21)(ESR1, MOG, and BDNF) and OLD(MOG and GABBR1) association with CY-BOCS baseline(B) CY-BOCS DIFFERENCE	Obsessive Compulsive Disorder	DNA methylation	Epigenome
190	27047397	9606	Blood	ICD-10	Case-control based	Illumina Infinium Human Methylation450 BeadChip	450K array	Table 5 Top hit genes from MVP analysis of NEW(N=21)(ESR1, MOG, and BDNF) and OLD(MOG and GABBR1) association with CY-BOCS baseline(C) TREATMENT RESPONDER	Obsessive Compulsive Disorder	DNA methylation	Epigenome
191	27074206	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Table.Genome-Wide Significant Schizophrenia-Associated DMPs	Schizophrenia	DNA methylation	Epigenome
192	27128683	9606	Brain	DSM-IV//AUDIT//OCDS-62//SCL-90-R	Case-control based	Pyrosequencing//PCR	Pyrosequencing//PCR	Our data add to the growing body of knowledge on epigenetic effects in alcohol dependence and supportGDAP1as a novel candidate gene implicated in this disorder.	Alcohol Use Disorder	DNA methylation	Epigenome
193	27128683	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	In the present study, we validate and replicate one of the top findings from this previous investigation in an independent cohort: the hypomethylation of GDAP1 in patients. To our knowledge, this is the first independent replication of an epigenome-wide finding in alcohol dependence.	Alcohol Use Disorder	DNA methylation	Epigenome
194	27134686	9606	Brain		Case-control based	ABI PRISM 7900HT Real-Time PCR//ABI 3500 XL Genetic Analyzer	RT-PCR//Genotyping	ASD patients display a significantly higher number of methylated CpG islands and heavier methylation in the 5芒鈧	Autism Spectrum Disorder	DNA methylation	Epigenome
195	27136348	10090	Brain	Others	Case-control based	MeDIP	MeDIP	Altered methylation and gene expression in oxidative stress pathways in the adult hippocampus suggests a novel interface between epigenetic and oxidative stress mechanisms in FASD	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
196	27136348	10090	Brain	Others	Case-control based	MeDIP	MeDIP	Altered methylation and gene expression in oxidative stress pathways in the adult hippocampus suggests a novel interface between epigenetic and oxidative stress mechanisms in FASD	Fetal Alcohol Spectrum Disorder	Histone modification	Epigenome
197	27175219	9606	Blood	DSM-IV-TR	Case-control based	Illumina 450K array	450K array	Additional file 7: Figure S3.DNA methylation levels for cg21149266, an Illumina 450 K methylation array probe in the region of interest in FAM63B across different blood cell types.	Bipolar Disorder	DNA methylation	Epigenome
198	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR2 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
199	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR3 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
200	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR4 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
201	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR5 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
202	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR6 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
203	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR7 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
204	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR8 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
205	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR9 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
206	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR10 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
207	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR11 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
208	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR12 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
209	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR13 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
210	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR14 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
211	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR15 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
212	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR16 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
213	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR17 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
214	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR18 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
215	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR19 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
216	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR20 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
217	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR21 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
218	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR22 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
219	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR23 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
220	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR24 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
221	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR25 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
222	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR26 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
223	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR27 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
224	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR28 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
225	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR29 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
226	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR30 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
227	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR31 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
228	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR32 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
229	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR33 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
230	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR34 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
231	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR35 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
232	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR36 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
233	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR37 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
234	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR38 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
235	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR39 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
236	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR40 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
237	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR128 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
238	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR42 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
239	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR41 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
240	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR43 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
241	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR44 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
242	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR45 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
243	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR46 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
244	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR47 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
245	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR48 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
246	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR49 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
247	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR50 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
248	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR51 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
249	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR52 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
250	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR53 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
251	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR54 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
252	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR81 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
253	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR82 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
254	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR83 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
255	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR84 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
256	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR85 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
257	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR86 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
258	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR87 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
259	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR88 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
260	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR89 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
261	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR63 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
262	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR64 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
263	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR65 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
264	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR66 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
265	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR67 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
266	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR68 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
267	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR69 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
268	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR70 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
269	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR93 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
270	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR90 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
271	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR91 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
272	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR92 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
273	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR94 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
274	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR103 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
275	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR100 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
276	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR101 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
277	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR102 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
278	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR104 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
279	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR105 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
280	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR106 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
281	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR107 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
282	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR108 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
283	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR109 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
284	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR110 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
285	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR116 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
286	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR117 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
287	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR118 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
288	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR119 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
289	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR120 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
290	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR121 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
291	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR122 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
292	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR123 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
293	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR124 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
294	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR125 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
295	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR126 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
296	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR127 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
297	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR55 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
298	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR56 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
299	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR57 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
300	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR58 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
301	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR59 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
302	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR60 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
303	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR61 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
304	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR62 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
305	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR95 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
306	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR96 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
307	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR97 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
308	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR98 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
309	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR99 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
310	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR71 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
311	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR72 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
312	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR73 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
313	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR74 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
314	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR75 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
315	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR76 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
316	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR77 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
317	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR78 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
318	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR79 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
319	27184921	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We identified 134 nutrition-sensitive, differentially methylated genomic regions, with most (87×) specific for generation 1. Multiple neuropsychiatric risk genes, including COMT, IFNG, MIR200B, SYNGAP1, and VIPR80 showed associations of specific methyl-CpGs with attention and IQ. IFNG expression was decreased in prefrontal cortex of rats showing attention deficits after developmental malnutrition.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
320	27184921	9606	Blood		Case-control based	Illumina 450k array	450K array	Supplemental Table S2: List of Differentially Methylated Regions(DMRs)	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
321	27184921	9606	Blood		Case-control based	Illumina 450k array	450K array	Supplemental Table S3: List of Differentially Methylated Regions(DMRs) G2CON_G2MAL	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
322	27184921	9606	Blood		Case-control based	Illumina 450k array	450K array	Supplemental Table S6: X-linked DNA methylation differences. Females only, G1CON_G1MAL	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
323	27217153	9606	Blood	DSM-IV	Family based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	In this study, we employed a methylome-wide prospective analysis (birth, age 7) with trajectories of ADHD symptoms (7-15 years). We identified 13 probes at birth that were differentially methylated between high and low trajectories of ADHD symptoms, none of which continued to be differentially methylated at age 7. Detected probes were located in the vicinity of genes implicated in peroxisomal processes, neural tube development and mental retardation, as well as one gene previously associated with ADHD. We first discuss our findings in light of the few previous epigenetic studies on ADHD, before turning to potentially relevant biological mechanisms suggested by our findings. We also discuss differences in results between birth and age 7 years from a developmental perspective.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
324	27217153	9606	Blood	DSM-IV	Family based	Illumina 450k array	450K array	Supplementary Table 4. Sensitivity analysis in a subsample with complete DNA methylation data at both time points(n=783) 	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
325	27309964	9606	Brain//Cell lines(SH-SH5Y/SH-SY5Y-15M)		Case-control based	Zymo's EZ DNA Methylation-Direct kit ona Pyromark Q24 Pyrosequencer(Qiagen)	Pyrosequencing//qRT-PCR//Western blotting	Although our findings indicate high frequency of OXTR promoter hypomethylation in ASDs, there is need for independent replication of the results for a bigger sample set. 	Autism Spectrum Disorder	DNA methylation	Epigenome
326	27358653	9606	Buccal epithelial cells	Others	Case-control based//Family based	Illumina HumanMethylation450 Array	Illumina HumanMethylation450 Array	After correcting for the effects of genetic background, we found 658 significantly differentially methylated sites between FASD cases and controls, with 41 displaying differences in percent methylation change >5 ×.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
327	27362416	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Significantly lower TRECs(p=0.004) as well as significant hypermethylation of the FOXP3 promoter region(p=0.005) were observed in female(but not in male) patients with panic disorder as compared to healthy controls.	Panic Disorder	DNA methylation	Epigenome
328	27367046	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Table 2. AN vs. LEAN: consensus CpG sites(P芒鈥奥	Anorexia Nervosa	DNA methylation	Epigenome
329	27367046	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Table 3. AN vs. POP: consensus CpG sites(P芒鈥奥	Anorexia Nervosa	DNA methylation	Epigenome
330	27527274	9606	Blood	DSM-IV	Case-control based	Illumina Infinium Human Methylation450 BeadChip	450K array	Table 3 Top 20 genes with high frequencies of methylation sites.	Obsessive Compulsive Disorder	DNA methylation	Epigenome
331	27535767	9606	Blood	Others	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	Participants were 164 youth with EOP (n = 83) versus low (n = 81) CP drawn from the Avon Longitudinal Study of Parents and Children. We assessed if the interrelationships between high-fat and -sugar diet (prenatal, postnatal), IGF2 methylation (birth and age 7, collected from blood), and ADHD symptoms (age 7-13) differed for EOP versus low CP youth.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
332	27535767	9606	Blood		Case-control based	Illumina 450k array	450K array	Appendix S1. Factor analysis procedure for reducing IGF2 methylation data and results.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
333	27602171	9606	Blood		Family based	Illumina 450K array	450K array	Supplementary Table 1: Significant regions detected by methylation array in ADCA-DN versus control individuals	Narcolepsy	DNA methylation	Epigenome
334	27685250	9606	Brain	Others	Case-control based	RT-PCR//TaqMan//Bisulphite Pyrosequencing	RT-PCR//TaqMan//Bisulphite Pyrosequencing	Our findings indicated that lower methylation rates may be a biomarker for DLB	Neurocognitive Disorder With Lewy Bodies	DNA methylation	Epigenome
335	27789384	10116	Blood//Brain		Case-control based	Bisulfite pyrosequencing	Bisulfite sequencing	A significant and selective increase of DNA methylation at CpG site number 2 of SERT gene was observed in "gambler" compared with "non-gambler" individuals in the PFC(unpaired t-test:t(10)=3.29, P=0.008; Figure 3a). 	Gambling Disorder	DNA methylation	Epigenome
336	27863250	9606	Brain		Case-control based	ChIP-seq	ChIP-seq	By correlating histone acetylation with genotype, we discovered >2,000 histone acetylation quantitative trait loci(haQTLs) in human brain regions, including four candidate causal variants for psychiatric diseases. 	Autism Spectrum Disorder	Histone modification	Epigenome
337	27903255	9606	Blood	DSM-IV//Y-BOCS	Case-control based		Bisulfite sequencing	We found that the level of methylation of the cytosine-phosphate-guanine sites in two targets sequences analyzed was greater in the OCD patients than in the controls. The higher methylation in the OCD patients correlated with OCD severity.Post-hoc analysis showed high confidence(>0.9) for a statement that the population median for all CpG sites of the OXTR 1 and OXTR 2 target sequences were lower in the healthy control group than in the OCD patients group(Table 2). 	Obsessive Compulsive Disorder	DNA methylation	Epigenome
338	27939640	10090	Spleen		Case-control based	Realplex2(Eppendorf) with the Green-2-Go qPCR Mastermix//Immunoblotting	qRT-PCR//Western blotting	Furthermore, H3K23 acetylation was not detectable in Brpf1-/- mouse embryonic fibroblasts(Figure 3F). By contrast, histone H3K9 and H3K14 acetylation was less consistently affected in different Brpf1-knockout samples(Figures 3A芒鈧€	Intellectual Disability	Histone modification	Epigenome
339	27939640	9606	Cell lines(Lymphoblastoid)		Case-control based	Realplex2(Eppendorf) with the Green-2-Go qPCR Mastermix//Immunoblotting	qRT-PCR//Western blotting	These data indicate that aberrations in the chromatin regulator gene BRPF1 cause histone H3 acetylation deficiency and a previously unrecognized intellectual disability syndrome.	Intellectual Disability	Histone modification	Epigenome
340	27974215	9606	Brain//Cell lines(SH-SH5Y/SH-SY5Y-15M)		Case-control based	Zymo's EZ DNA Methylation-Direct kit ona Pyromark Q24 Pyrosequencer(Qiagen)	Pyrosequencing//qRT-PCR//Western blotting	These results demonstrate the compounding effects of genetic and environmental insults on the neuronal methylome that converge upon dysregulation of chromatin and synaptic genes.(Supplemental Table 9. Culture PMD gene list, related to Figure 2(Hypo_PCB_shortterm))	Autism Spectrum Disorder	DNA methylation	Epigenome
341	28117656	9606	Brain	DSM-IV	Case-control based	Illumina 450K array	450K array	We analyzed the previously published DNA methylation profiles of prefrontal cortex from 335 healthy controls and 191 schizophrenic patients.(Additional file 1: Differentially methylated genes with differential expression databases.)	Schizophrenia	DNA methylation	Epigenome
342	28149334	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Table 1 Probes with significant differential DNA methylation status between PD and control	Panic Disorder	DNA methylation	Epigenome
343	28292649	9606	Blood	DSM-IV	Case-control based	Bisulfite sequencing 	Bisulfite sequencing 	The overall methylation levels across NR3C1 1F promoter(P<0.0001) and percent methylation at each of the 5 CpG sites including CpG12, 21, 30, 31, and 32(P<0.001) significantly increased. 	Generalized Anxiety Disorder	DNA methylation	Epigenome
344	28299627	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Our study indicates that the epigenetic dysregulation of ESR2 may govern the development of autism.	Autism Spectrum Disorder	DNA methylation	Epigenome
345	28485403	9606	Brain(DLPFC)//Cell lines(HEK293)		Case-control based	Customized TaqMan Gene Expression Assays//Illumina HumanMethylation450 BeadChip Kit	450K array//RT-PCR//TaqMan	In addition, methylation levels of two CpG loci within the putative GAD1 promoter were significantly associated with the schizophrenia-risk SNP rs3749034 and with the expression of GAD25 in dorsolateral prefrontal cortex(DLPFC). 	Schizophrenia	DNA methylation	Epigenome
346	28505127	9606	Brain	DSM-IV	Case-control based	Illumina 450K array	450K array	Samples consisted of postmortem human hippocampus tissue from eight schizophrenia patients, eight bipolar disorder patients, and eight healthy control subjects. Within these genomic regions, we observed far greater difference in methylation patterns between circuit locations within subjects than in a single subregion between subjects across diagnostic groups, demonstrating the complexity of genotype to phenotype elaboration across the diverse circuitry of the human brain.	Schizophrenia	DNA methylation	Epigenome
347	28505127	9606	Brain	DSM-IV	Case-control based	Illumina 450K array	450K array	Samples consisted of postmortem human hippocampus tissue from eight schizophrenia patients, eight bipolar disorder patients, and eight healthy control subjects. Within these genomic regions, we observed far greater difference in methylation patterns between circuit locations within subjects than in a single subregion between subjects across diagnostic groups, demonstrating the complexity of genotype to phenotype elaboration across the diverse circuitry of the human brain.	Bipolar Disorder	DNA methylation	Epigenome
348	28505127	9606	Brain	DSM-IV	Case-control based	Illumina 450K array	450K array	Table 3 Distribution and overlap of differentially methylated regions among circuit location comparisons.	Schizophrenia	DNA methylation	Epigenome
349	28540928	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Interestingly, one of the other CpG sites(cg21650243) upstream of this CpG of interest showed significant interactions with IL-18 levels in mildly anxious participants(total, p=0.052; women p=0.007) but here, mild anxiety was inversely associated with methylation, in the total population and in women(Table 3b). 	Anxiety Disorder	DNA methylation	Epigenome
350	28540928	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Three other CpG sites showed significant differences between panic cases and controls(cg21650243: 脦虏=0.323, SE=0.162, p=0.047; cg00708580: 脦虏=0.490, SE=0.191, p=0.011; cg14380745: 脦虏=0.477, SE=0.238, p=0.046).	Panic Disorder	DNA methylation	Epigenome
351	28540928	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	A tendency towards a significant interaction between IL-18 and severe anxiety on methylation changes at CpG site cg12701571 was observed in the total population(p=0.08) and amoung women, a significant interaction was observed(p=0.014)(see Table 3a).	Anxiety Disorder	DNA methylation	Epigenome
352	28630453	9606	Brain	SRIP//ETISR-SF//SCL-90-R//CAPS	Case-control based	Illumina HumanMethylation450 BeadChip//Pyrosequencing	Illumina HumanMethylation450 BeadChip//Pyrosequencing	In order to determine the impact of the epigenetic response to traumatic stress on post-traumatic stress disorder (PTSD), this study examined longitudinal changes of genome-wide blood DNA methylation profiles in relation to the development of PTSD symptoms in two prospective military cohorts (one discovery and one replication data set).	Posttraumatic Stress Disorder	DNA methylation	Epigenome
353	28630453	9606	Brain	SRIP//ETISR-SF//SCL-90-R//CAPS	Case-control based	Illumina HumanMethylation450 BeadChip//Pyrosequencing	Illumina HumanMethylation450 BeadChip//Pyrosequencing	Together, our study pinpoints three novel genomic regions where longitudinal decreases in DNA methylation across the period of exposure to combat trauma marks susceptibility for PTSD.	Posttraumatic Stress Disorder	DNA methylation	Epigenome
354	28654093	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Table 3. Top ranking CpG sites for PTSD and MDD and at nominal P-value 0.0001	Major Depressive Disorder	DNA methylation	Epigenome
355	28654093	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Table 3. Top ranking CpG sites for PTSD and MDD and at nominal P-value 0.0001	Posttraumatic Stress Disorder	DNA methylation	Epigenome
356	28781890	9606	Placenta	DSM-IV//DSM-5	Case-control based	Illumina 450K array	450K array	In the subset with genotype data available, maternal MTHFR 677 CT/TT genotype was associated with higher PMD methylation after adjustment for other factors selected by best model fit(Table 2), and after adjustment for HMD methylation(P=0.01), but was not significant after FDR correction(Table 2). 	Autism Spectrum Disorder	DNA methylation	Epigenome
357	28848234	9606	Brain	SCID//ADS//CIWA-Ar	Case-control based	Illumina HumanMethylation450 BeadChip//Pyrosequencing//RT-qPCR	Illumina HumanMethylation450 BeadChip//Pyrosequencing//RT-qPCR	Replication in AUD datasets confirmedPCSK9hypomethylation and a translational mouse model of AUD showed that alcohol exposure leads toPCSK9downregulation.	Alcohol Use Disorder	DNA methylation	Epigenome
358	28850114	9606	Blood	ICD-10	Case-control based	Illumina 450K array	450K array	In conclusion, our study suggests an association of DNA methylation differences at birth with development of mental disorder later in life in 22q11.2DS individuals.(Table 1 Overview of findings with P-value<10-6 obtained from EWAS analysis of psychiatric phenotypes in individuals with 22q11.2DS)	Psychotic Disorder	DNA methylation	Epigenome
359	28850114	9606	Blood	ICD-10	Case-control based	Illumina 450K array	450K array	In conclusion, our study suggests an association of DNA methylation differences at birth with development of mental disorder later in life in 22q11.2DS individuals.(Table 1 Overview of findings with P-value<10-6 obtained from EWAS analysis of psychiatric phenotypes in individuals with 22q11.2DS)	Neurodevelopmental Disorders	DNA methylation	Epigenome
360	28850114	9606	Blood	ICD-10	Case-control based	Illumina 450K array	450K array	In conclusion, our study suggests an association of DNA methylation differences at birth with development of mental disorder later in life in 22q11.2DS individuals.(Table 1 Overview of findings with P-value<10-6 obtained from EWAS analysis of psychiatric phenotypes in individuals with 22q11.2DS)	Intellectual Disability	DNA methylation	Epigenome
361	28850114	9606	Blood	ICD-10	Case-control based	Illumina 450K array	450K array	In conclusion, our study suggests an association of DNA methylation differences at birth with development of mental disorder later in life in 22q11.2DS individuals.(Table 1 Overview of findings with P-value<10-6 obtained from EWAS analysis of psychiatric phenotypes in individuals with 22q11.2DS)	Schizophrenia	DNA methylation	Epigenome
362	28929496	9606	Blood	Others	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	With respect to the biological pathways analysis, we found that 108 genes overlapped between ODD and ADHD (p < .001 across both phenotypes). With regard to headstrong, we found that 57 genes overlapped with ADHD (p < .001 across both phenotypes). We also examined the overlap of the 108 ODD-ADHD genes and 57 headstrong-ADHD genes. A total of 15 genes were common between ODD, headstrong, and ADHD.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
363	28929496	9606	Blood	DAWBA//DSM-ｍ	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	We did examine the overlap in DNA methylation of loci associated with ODD and headstrong and ADHD in two ways: (a) overlap in top FDR corrected hits between the two phenotypes, and (b) a gene ontology overlap analysis based on loci that were significant at p < .01 for each construct.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
364	29028941	9606	Brain	DSM-5	Family based	Illumina 450K array	450K array	Table 1 Top 25 DMRs detected in cortical neuronal nuclei between ASD and control groups.	Autism Spectrum Disorder	DNA methylation	Epigenome
365	29106553	9606	Blood	DSM-V	Case-control based	Illumina 450K array	450K array	A total of 27 CpG sites were differentially methylated in IED participants(P<5.0脙鈥	Intermittent Explosive Disorder	DNA methylation	Epigenome
366	29131015	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Table 2. Top10 ranking of differentially methylated CpG sites between BR and WR	Major Depressive Disorder	DNA methylation	Epigenome
367	29160620	9606	Blood	DSM-IV	Case-control based	MethyLight//Bisulfite sequencing	Bisulfite sequencing//RT-PCR//Taqman	The percentage methylation ratio of COMT was lower in schizophrenia than it was in the healthy controls(P<0.001) and was different between the body mass index(P=0.003) and antipsychotic(P=0.004) groups.	Schizophrenia	DNA methylation	Epigenome
368	29249830	9606	Blood	DSM-IV	Case-control based	Illumina 450K array	450K array	Table 2 Targeted gene analysis results for the significant CpGs	Panic Disorder	DNA methylation	Epigenome
369	29256967	9606	Saliva	DSM-IV	Case-control based	Bisulfite pyrosequencing	Bisulfite sequencing	We found that three CpGs were nominally associated with AN(P=0.02-0.03); the largest difference was a 9% hypermethylation in AN. One CpG was nominally associated with BN(P=0.04), with 4% hypomethylation. 	Anorexia Nervosa	DNA methylation	Epigenome
370	29256967	9606	Saliva	DSM-IV	Case-control based	Bisulfite pyrosequencing	Bisulfite sequencing	We found that three CpGs were nominally associated with AN(P=0.02-0.03); the largest difference was a 9% hypermethylation in AN. One CpG was nominally associated with BN(P=0.04), with 4% hypomethylation. 	Bulimia Nervosa	DNA methylation	Epigenome
371	29344313	9606	Blood		Case-control based	Illumina 450K array	450K array	We validated findings from our previous study that identified a DNA methylation signature of FASD, replicating the altered DNA methylation levels of 161/648 CpGs in this independent cohort, which may represent a robust signature of FASD in the epigenome.(St2)	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
372	29344313	9606	Blood		Case-control based	Illumina 450K array	450K array	Table 2 Genes containing multiple differentially methylated CpGs in FASD	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
373	29430824	9606	Blood	DSM-IV	Case-control based	Pyrosequencing assay	Pyrosequencing//RT-PCR	Table 1 Results of DNA methylation analyses for SZ MWAS findings at the the top five candidate regions in BD	Bipolar Disorder	DNA methylation	Epigenome
374	29430824	9606	Blood	DSM-IV	Case-control based	Pyrosequencing assay	Pyrosequencing//RT-PCR	Table 1 Results of DNA methylation analyses for SZ MWAS findings at the the top five candidate regions in BD	Schizophrenia	DNA methylation	Epigenome
375	29544979	9606	Brain	Others	Case-control based	Bisulfite Pyrosequencing	Bisulfite Pyrosequencing	APOEDNA methylation was significantly reduced in npLBD compared to npControls, and methylation levels were lowest in the LBD + AD group.	Neurocognitive Disorder With Lewy Bodies	DNA methylation	Epigenome
376	29988321	9606	Blood	ADOS//ADI-R	Case-control based	Illumina HumanMethylation450 BeadChip//Meta-analysis	Illumina HumanMethylation450 BeadChip//Meta-analysis	In this meta-analysis of blood-based DNA from 796 cases and 858 controls, no single CpG met a Bonferroni discovery threshold ofp<1.12℅107. Seven CpGs showed differences atp<1℅105and 48 at 1℅104.	Autism Spectrum Disorder	DNA methylation	Epigenome
377	30134995	9606	Brain	IPDE//DSM-IV//BSL23//SCL90R//CTQ	Case-control based	PCR//Pyrosequencing	PCR//Pyrosequencing	In the present study, we analyzed DNA methylation of theBDNFIV promoter in saliva and blood of 41 BPD patients and 41 matched healthy controls and found significant hypermethylation in the BPD patient＊s saliva, but not blood.	Borderline Personality Disorder	DNA methylation	Epigenome
378	30135428	9606	Buccal epithelial cells	CIDI	Case-control based	MBD-seq	MBD-seq	Using sequencing-based data from 1132 major depressive disorder (MDD) cases and controls, we performed a MWAS of 970,414 common CpG-SNPs. The analysis identified 27 suggestively significant (P < 1.00 ℅ 10-5) CpG-SNPs associations.	Major Depressive Disorder	DNA methylation	Epigenome
379	30242228	9606	Buccal epithelial cells	DSM-IV	Case-control based	MBD-seq	MBD-seq	We present the first large-scale methylome-wide association studies (MWAS) for Major Depressive Disorderr (MDD) to identify sites of potential importance for MDD etiology. Using a sequencing-based approach that provides near-complete coverage of all 28 million common CpGs in the human genome, we assay methylation in MDD cases and controls from both blood (N = 1132) and postmortem brain tissues (N = 61 samples from Brodmann Area 10, BA10).	Major Depressive Disorder	DNA methylation	Epigenome
380	30242228	9606	Brain(Ventral striatum)	DSM-IV	Case-control based	MBD-seq	MBD-seq	We present the first large-scale methylome-wide association studies (MWAS) for Major Depressive Disorderr (MDD) to identify sites of potential importance for MDD etiology. Using a sequencing-based approach that provides near-complete coverage of all 28 million common CpGs in the human genome, we assay methylation in MDD cases and controls from both blood (N = 1132) and postmortem brain tissues (N = 61 samples from Brodmann Area 10, BA10).	Major Depressive Disorder	DNA methylation	Epigenome
381	30242228	9606	Brain(Putamen)	DSM-IV	Case-control based	MBD-seq	MBD-seq	We present the first large-scale methylome-wide association studies (MWAS) for Major Depressive Disorderr (MDD) to identify sites of potential importance for MDD etiology. Using a sequencing-based approach that provides near-complete coverage of all 28 million common CpGs in the human genome, we assay methylation in MDD cases and controls from both blood (N = 1132) and postmortem brain tissues (N = 61 samples from Brodmann Area 10, BA10).	Major Depressive Disorder	DNA methylation	Epigenome
382	30242228	9606	Brain(Ventral tegmental area)	DSM-IV	Case-control based	MBD-seq	MBD-seq	We present the first large-scale methylome-wide association studies (MWAS) for Major Depressive Disorderr (MDD) to identify sites of potential importance for MDD etiology. Using a sequencing-based approach that provides near-complete coverage of all 28 million common CpGs in the human genome, we assay methylation in MDD cases and controls from both blood (N = 1132) and postmortem brain tissues (N = 61 samples from Brodmann Area 10, BA10).	Major Depressive Disorder	DNA methylation	Epigenome
383	30242228	9606	Brain//Blood	DSM-IV	Case-control based	MBD-seq	MBD-seq	We present the first large-scale methylome-wide association studies (MWAS) for Major Depressive Disorderr (MDD) to identify sites of potential importance for MDD etiology. Using a sequencing-based approach that provides near-complete coverage of all 28 million common CpGs in the human genome, we assay methylation in MDD cases and controls from both blood (N = 1132) and postmortem brain tissues (N = 61 samples from Brodmann Area 10, BA10).	Major Depressive Disorder	DNA methylation	Epigenome
384	30439595	9606	Brain	Others	Case-control based	Bisulfite Pyrosequencing	Bisulfite Pyrosequencing	Our data suggest that ANK1 is characterized by region and disease-specific differential DNA methylation in multiple neurodegenerative diseases.	Neurocognitive Disorder With Lewy Bodies	DNA methylation	Epigenome
385	30465968	9606	Brain	DSM-IV	Case-control based	PCR//Pyrosequencing//Ion Torrent	PCR//Pyrosequencing//Ion Torrent	The methylation analysis of the ARNTL CG site cg05733463 was performed by bisulfite treatment of genomic DNA with the Epitect kit, PCR and pyrosequencing. Additionally, DNA was extracted from stool samples and subjected to 16S rRNA sequencing. QIIME was used to analyze microbiome data. Results Methylation status of the ARNTL CpG position cg05733463 correlated significantly with bacterial diversity (Simpson index: r= -0.389, p = 0.0238) and evenness (Simpson evenness index: r= -0.358, p = 0.044).	Bipolar Disorder	DNA methylation	Epigenome
386	30635639	9606	Brain	Others	Case-control based	Illumina HumanMethylation450 Array	Illumina HumanMethylation450 Array	The methylation analysis of the ARNTL CG site cg05733463 was performed by bisulfite treatment of genomic DNA with the Epitect kit, PCR and pyrosequencing. Additionally, DNA was extracted from stool samples and subjected to 16S rRNA sequencing. QIIME was used to analyze microbiome data. Results Methylation status of the ARNTL CpG position cg05733463 correlated significantly with bacterial diversity (Simpson index: r= -0.389, p = 0.0238) and evenness (Simpson evenness index: r= -0.358, p = 0.044).	Schizophrenia	DNA methylation	Epigenome
387	30665597	10116	Buccal epithelial cells	Others	Case-control based	RNA-seq//ChIP//PCR	RNA-seq//ChIP//PCR	Our results demonstrate that CDYL-mediated histone crotonylation plays a critical role in regulating stress-induced depression, providing a potential therapeutic target for major depressive disorder.	Major Depressive Disorder	Histone modification	Epigenome
388	30873861	9606	Brain(Caudate nucleus)	Others	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	We identified several loci that were robustly associated with FASD or one of its sub phenotypes.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
389	30873861	9606	Brain(Hippocampus)	Others	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	We identified several loci that were robustly associated with FASD or one of its sub phenotypes.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
390	30873861	9606	Brain(Frontal cortex)	Others	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	We identified several loci that were robustly associated with FASD or one of its sub phenotypes.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
391	30873861	9606	Brain(Dorsolateral prefrontal cortex)	Others	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	We identified several loci that were robustly associated with FASD or one of its sub phenotypes.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
392	30873861	9606	Brain(Frontal lobe//Cerebellum)	Others	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	We identified several loci that were robustly associated with FASD or one of its sub phenotypes.	Fetal Alcohol Spectrum Disorder	DNA methylation	Epigenome
393	30900359	9606	Blood	Others	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	We identified a total of 105 DMRs in 76 autism cases (25.6× of all autism cases) (Aut-DMRs) and 309 DMRs in 220 schizophrenia cases (28.6× of all schizophrenia cases) (Scz-DMRs) (Supp. Tables S1andS2).	Schizophrenia	DNA methylation	Epigenome
394	30900359	9606	Blood	Others	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	We identified a total of 105 DMRs in 76 autism cases (25.6× of all autism cases) (Aut-DMRs) and 309 DMRs in 220 schizophrenia cases (28.6× of all schizophrenia cases) (Scz-DMRs) (Supp. Tables S1andS2).	Autism Spectrum Disorder	DNA methylation	Epigenome
395	30929061	9606	Saliva	ICD-10//MADRS//YMRS	Case-control based	Pyrosequencing	Pyrosequencing	We found a significant difference of methylation levels at CpG site 1-1-1 and 3-1-1 between MDD and healthy controls (p < 0.003) with MDD patients showing significantly higher methylation levels.	Major Depressive Disorder	DNA methylation	Epigenome
396	30929061	9606	Brain	ICD-10	Case-control based	KASP//PCR//ELISA	KASP//PCR//ELISA	This study aimed at investigating the BDNF val66met genotype, BDNF DNA methylation changes and peripheral BDNF serum levels in acute and remitted phases of MDD (major depressive disorder) and BD (bipolar disorder) and healthy controls.	Bipolar Disorder	DNA methylation	Epigenome
397	31031654	9606	Brain	SIAB-EX//DSM-IV	Case-control based	Bisulfite Sequencing	Bisulfite Sequencing	We found a lower DNA methylation of theLEPgene promoter in acute AN compared to controls and, in line with our expectations, a DNA hypomethylation of theLEPRgene promoter.	Anorexia Nervosa	DNA methylation	Epigenome
398	31220268	9606	Blood	Others	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	Our study represents the first systematic analysis of DNA methylation associated with ASD across multiple brain regions, providing novel evidence for convergent molecular signatures associated with both idiopathic and syndromic autism	Autism Spectrum Disorder	DNA methylation	Epigenome
399	31239533	9606	Brain	DSM-IV	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip//Methyl-DNA–Immunoprecipitation Assay//ChIP Assay//qRT-PCR//Western Blotting	Illumina Infinium HumanMethylationEPIC BeadChip//Methyl-DNA–Immunoprecipitation Assay//ChIP Assay//qRT-PCR//Western Blotting	These data suggest that alcohol-dependent aberrant DNA methylation ofNR3C1and consequent changes in other stress-related genes might be fundamental in the pathophysiology of AUD and lay the groundwork for treatments targeting the epigenetic mechanisms regulatingNR3C1in AUD.	Alcohol Use Disorder	DNA methylation	Epigenome
400	31279243	9606	Brain	DSM-IV	Case-control based	Illumina Infinium HumanMethylationEPIC850 BeadChip//RT-qPCR	Illumina Infinium HumanMethylationEPIC850 BeadChip//RT-qPCR	Dorsolateral prefrontal cortex (DLPFC) and temporal pole (TP) are brain regions that display abnormalities in bipolar disorder (BD) patients. To study BD-associated DNA methylomic differences in these brain regions, we extracted genomic DNA from the postmortem tissues of Brodmann Area (BA) 9 (DLPFC) and BA38 (TP) gray matter from 20 BD, ten major depression (MDD), and ten control age-and-sex-matched subjects.	Bipolar Disorder	DNA methylation	Epigenome
401	31279243	9606	Brain	DSM-IV	Case-control based	Illumina Infinium HumanMethylationEPIC850 BeadChip	Illumina Infinium HumanMethylationEPIC850 BeadChip	Dorsolateral prefrontal cortex (DLPFC) and temporal pole (TP) are brain regions that display abnormalities in bipolar disorder (BD) patients. To study BD-associated DNA methylomic differences in these brain regions, we extracted genomic DNA from the postmortem tissues of Brodmann Area (BA) 9 (DLPFC) and BA38 (TP) gray matter from 20 BD, ten major depression (MDD), and ten control age-and-sex-matched subjects.	Bipolar Disorder	DNA methylation	Epigenome
402	31379624	9606	Blood	DSM-IV//K-SADS-PL	Case-control based	qPCR//MSP	qPCR//MSP	There was a significant difference in the methylation ratio ofPPARGC1Aamong ADHD subtypes. These results suggest the possible involvement of mitochondrial dysfunction in the pathophysiology of ADHD	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
403	31451081	9606	Blood	Others	Case-control based	Reduced Representation Bisulphite Sequencing	Reduced Representation Bisulphite Sequencing	DLGAP2, a membrane-associated protein located in the post-synaptic density of neurons, plays a key role in synapse organization and neuronal signaling. Dysregulation of DLGAP2 is associated with various neurological and psychiatric disorders, such as Autism Spectrum Disorder (ASD) and schizophrenia.This genome-scale analysis identified CpG sites that were differentially methylated in the sperm of cannabis users compared to controls. Results for nine CpG sites, intronically located in DLGAP2, that were significantly hypomethylated in the sperm of cannabis users compared to controls.	Autism Spectrum Disorder	DNA methylation	Epigenome
404	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).5).	Major Depressive Disorder	DNA methylation	Epigenome
405	31477685	9606	Semen	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).36).	Major Depressive Disorder	DNA methylation	Epigenome
406	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).27).	Major Depressive Disorder	DNA methylation	Epigenome
407	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).3).	Major Depressive Disorder	DNA methylation	Epigenome
408	31477685	9606	Semen	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).33).	Major Depressive Disorder	DNA methylation	Epigenome
409	31477685	9606	Semen	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).34).	Major Depressive Disorder	DNA methylation	Epigenome
410	31477685	9606	saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).21).	Major Depressive Disorder	DNA methylation	Epigenome
411	31477685	9606	saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).18).	Major Depressive Disorder	DNA methylation	Epigenome
412	31477685	9606	saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).16).	Major Depressive Disorder	DNA methylation	Epigenome
413	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).9).	Major Depressive Disorder	DNA methylation	Epigenome
414	31477685	9606	Feces	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).37).	Major Depressive Disorder	DNA methylation	Epigenome
415	31477685	9606	Semen	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).29).	Major Depressive Disorder	DNA methylation	Epigenome
416	31477685	9606	saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).26).	Major Depressive Disorder	DNA methylation	Epigenome
417	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).7).	Major Depressive Disorder	DNA methylation	Epigenome
418	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).4).	Major Depressive Disorder	DNA methylation	Epigenome
419	31477685	9606	saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).23).	Major Depressive Disorder	DNA methylation	Epigenome
420	31477685	9606	saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).24).	Major Depressive Disorder	DNA methylation	Epigenome
421	31477685	9606	Semen	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).35).	Major Depressive Disorder	DNA methylation	Epigenome
422	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).12).	Major Depressive Disorder	DNA methylation	Epigenome
423	31477685	9606	Blood(monocytes)	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).38).	Major Depressive Disorder	DNA methylation	Epigenome
424	31477685	9606	Semen	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).31).	Major Depressive Disorder	DNA methylation	Epigenome
425	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).10).	Major Depressive Disorder	DNA methylation	Epigenome
426	31477685	9606	Blood(monocytes)	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).40).	Major Depressive Disorder	DNA methylation	Epigenome
427	31477685	9606	Semen	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).28).	Major Depressive Disorder	DNA methylation	Epigenome
428	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).8).	Major Depressive Disorder	DNA methylation	Epigenome
429	31477685	9606	saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).17).	Major Depressive Disorder	DNA methylation	Epigenome
430	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).2).	Major Depressive Disorder	DNA methylation	Epigenome
431	31477685	9606	saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).22).	Major Depressive Disorder	DNA methylation	Epigenome
432	31477685	9606	saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).20).	Major Depressive Disorder	DNA methylation	Epigenome
433	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).15).	Major Depressive Disorder	DNA methylation	Epigenome
434	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).6).	Major Depressive Disorder	DNA methylation	Epigenome
435	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).25).	Major Depressive Disorder	DNA methylation	Epigenome
436	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).14).	Major Depressive Disorder	DNA methylation	Epigenome
437	31477685	9606	Saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).13).	Major Depressive Disorder	DNA methylation	Epigenome
438	31477685	9606	Blood(monocytes)	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).39).	Major Depressive Disorder	DNA methylation	Epigenome
439	31477685	9606	saliva	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).19).	Major Depressive Disorder	DNA methylation	Epigenome
440	31477685	9606	Semen	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).32).	Major Depressive Disorder	DNA methylation	Epigenome
441	31477685	9606	Semen	SCID-4-RV//BDI-II	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We identified 39 DMRs (annotated to 36 unique genes) significantly associated with MDD atq<0.05 (Table(Table2).30).	Major Depressive Disorder	DNA methylation	Epigenome
442	31501512	9606	Brain(Putamen)	DSM-IV	Case-control based	MBD-seq	MBD-seq	We associated blood DNA methylation profiles from 581 MDD patients at baseline with MDD status 6 years later. A resampling approach showed a highly significant association between methylation profiles in blood at baseline and future disease status (P = 2.0 ℅ 10-16). Top MWAS results were enriched specific pathways, overlapped with genes found in GWAS of MDD disease status, autoimmune disease and inflammation, and co-localized with eQTLS and (genic enhancers of) of transcription sites in brain and blood.	Major Depressive Disorder	DNA methylation	Epigenome
443	31501512	9606	Brain(Prefrontal cortex)	DSM-IV	Case-control based	MBD-seq	MBD-seq	We associated blood DNA methylation profiles from 581 MDD patients at baseline with MDD status 6 years later. A resampling approach showed a highly significant association between methylation profiles in blood at baseline and future disease status (P = 2.0 ℅ 10-16). Top MWAS results were enriched specific pathways, overlapped with genes found in GWAS of MDD disease status, autoimmune disease and inflammation, and co-localized with eQTLS and (genic enhancers of) of transcription sites in brain and blood.	Major Depressive Disorder	DNA methylation	Epigenome
444	31530416	9606	Brain	ICD-10//DSM-IV//OCDS//BDI//AUDIT	Case-control based	Bisulfite Sequencing	Bisulfite Sequencing	As in other types ofaddictive disorders, DRD2-gene methylation is altered during alcohol withdrawal/early abstinence.	Alcohol Withdrawal	DNA methylation	Epigenome
445	31659741	9606	Brain	Others	Case-control based	PCR	PCR	This is the first report showing that DRD2 DNA methylation rates in leukocytes were increased in DLB patients and decreased in PD patients.	Neurocognitive Disorder With Lewy Bodies	DNA methylation	Epigenome
446	31754096	9606	Brain	SCID-I//DSM-IV	Case-control based	EWAS//Illumina HumanMethylationEPIC Beadchip	EWAS//Illumina HumanMethylationEPIC Beadchip	Table2 Differentially methylated CpG sites with suggestive significance (p<1E-5) in patients with panic disorder as compared to healthy controls.	Panic Disorder	DNA methylation	Epigenome
447	31804778	9606	Brain	Others	Case-control based	Bisulfite Pyrosequencing	Bisulfite Pyrosequencing	This study sheds light on the neurobiological process of how epigenetic variation in the SLC6A4 gene may relate to rsFC in the salience network that is linked to psychopathology in anorexia nervosa.	Anorexia Nervosa	DNA methylation	Epigenome
448	31889537	9606	Embryos	Others	Case-control based	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	The MWAS for monocytes yielded 904 methylome-wide significant CpGs (TableS14inSupplement 2).	Major Depressive Disorder	DNA methylation	Epigenome
449	31889537	9606	Cell lines(NS-5 Neural stem cells)	Others	Case-control based	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	The MWAS for monocytes yielded 904 methylome-wide significant CpGs (TableS14inSupplement 2).	Major Depressive Disorder	DNA methylation	Epigenome
450	31889537	9606	Buccal epithelial cells	Others	Case-control based	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	The MWAS for monocytes yielded 904 methylome-wide significant CpGs (TableS14inSupplement 2).	Major Depressive Disorder	DNA methylation	Epigenome
451	31889537	9606	Cell lines(DRG-derived neural stem cells)	Others	Case-control based	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	The MWAS for monocytes yielded 904 methylome-wide significant CpGs (TableS14inSupplement 2).	Major Depressive Disorder	DNA methylation	Epigenome
452	31889537	9606	Saliva	Others	Case-control based	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	In T cells, 9 CpGs passed methylome-wide significance (TableS17inSupplement 2)	Major Depressive Disorder	DNA methylation	Epigenome
453	31889537	9606	Saliva	Others	Case-control based	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	The MWAS for monocytes yielded 904 methylome-wide significant CpGs (TableS14inSupplement 2).	Major Depressive Disorder	DNA methylation	Epigenome
454	31889537	9606	Embryos	Others	Case-control based	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	Only one intergenic site in whole blood passed theFDRthreshold of 0.1	Major Depressive Disorder	DNA methylation	Epigenome
455	31889537	9606	Cell lines(DRG-derived neural stem cells)	Others	Case-control based	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	Only one intergenic site in whole blood passed theFDRthreshold of 0.1	Major Depressive Disorder	DNA methylation	Epigenome
456	31889537	9606	Cell lines(NS-5 Neural stem cells)	Others	Case-control based	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	Only one intergenic site in whole blood passed theFDRthreshold of 0.1	Major Depressive Disorder	DNA methylation	Epigenome
457	31889537	9606	Buccal epithelial cells	Others	Case-control based	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	Only one intergenic site in whole blood passed theFDRthreshold of 0.1	Major Depressive Disorder	DNA methylation	Epigenome
458	31889537	9606	Saliva	Others	Case-control based	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	MBD-seq//Illumina Infinium HumanMethylation450 Beadchip	Only one intergenic site in whole blood passed theFDRthreshold of 0.1	Major Depressive Disorder	DNA methylation	Epigenome
459	31931508	9606	Blood	DSM-ｍ//ADI-R//ADOS-2	Case-control based	EpiTYPER MassARRAY	EpiTYPER MassARRAY	Taken together, these findings provide initial evidence for OXTR hypermethylation in the intron area as a potential biomarker for adults with ASD with less severe developmental communication deficits, but with impairments in theory of mind and self-awareness.	Autism Spectrum Disorder	DNA methylation	Epigenome
460	31931860	9606	Brain	PCL//CIDI-SC	Case-control based	Illumina HumanMethylation450 BeadChip//Meta-analysis	Illumina HumanMethylation450 BeadChip//Meta-analysis	Four genome-wide significant CpG sites (i.e., differentially methylated positions, DMPs) were identified using a conservative Bonferroni threshold ofp= 1.13 ℅ 1007for the 450K EWAS array (Table(Table2).2).	Posttraumatic Stress Disorder	DNA methylation	Epigenome
461	31931860	9606	Brain	PCL//CIDI-SC	Case-control based	Illumina HumanMethylation450 BeadChip//Meta-analysis	Illumina HumanMethylation450 BeadChip//Meta-analysis	Furthermore, 12 DMRs were identified (Additional file1: Figures S7-18, Fig.Fig.1),1), 7 of which were also significant in stage 1 and 4 were located in the human leukocyte antigen (HLA) region (Table(Table33).	Posttraumatic Stress Disorder	DNA methylation	Epigenome
462	31977880	9606	Blood	DSM-ｍ//CARS//ABC	Case-control based	qMSP	qMSP	Our study suggested that hypomethylation of the HTR4 promoter is a potential biomarker for predicting the risk of male ASD.	Autism Spectrum Disorder	DNA methylation	Epigenome
463	32080920	9606	Brain	DSM-IV//CIWA-Ar	Case-control based	Illumina EPIC BeadChip	Illumina EPIC BeadChip	Table S1?CpG sites significantly associated with withdrawal state in patients after FDR correction.	Alcohol Use Disorder	DNA methylation	Epigenome
464	32080920	9606	Brain	DSM-IV//CIWA-Ar	Case-control based	Illumina EPIC BeadChip//Illumina HiScan Array	Illumina EPIC BeadChip//Illumina HiScan Array	Table S1?CpG sites significantly associated with withdrawal state in patients after FDR correction.	Alcohol Use Disorder	DNA methylation	Epigenome
465	32109418	9606	Blood	Others	Case-control based	Illumina HumanMethylation450 BeadChip//Illumina Infinium HumanMethylationEPIC BeadChip	Illumina HumanMethylation450 BeadChip//Illumina Infinium HumanMethylationEPIC BeadChip	We present here an approach to episignature mapping in 42 genetic syndromes, which has allowed the identification of 34 robust disease-specific episignatures. We examine emerging patterns of overlap, as well as similarities and hierarchical relationships across these episignatures, to highlight their key features as they are related to genetic heterogeneity, dosage effect, unaffected carrier status, and incomplete penetrance.	Neurodevelopmental Disorders	DNA methylation	Epigenome
466	32133483	9606	Brain	Y-BOCS//SCID-I	Case-control based	EpiTect 96 Bisulfite Kit	EpiTect 96 Bisulfite Kit	Significantly lowerMAOApromoter methylation was discerned in obsessive-compulsive disorder patients relative to healthy controls.	Obsessive Compulsive Disorder	DNA methylation	Epigenome
467	32171335	9606	Brain	Others	Case-control based	Illumina HumanMethylation450 BeadChip//Illumina EPIC850 BeadChip	Illumina HumanMethylation450 BeadChip//Illumina EPIC850 BeadChip	The cross replication observed in independent cohorts is evidence that DNA methylation in peripheral tissue can yield consistent and replicable PTSD associations	Posttraumatic Stress Disorder	DNA methylation	Epigenome
468	32218500	9606	Brain	DSM-IV-TR//BIS//mPCCTS//BAI	Case-control based	Pyrosequencing	Pyrosequencing	Our findings indicate that altered methylation ofPPM1Gmay influence the impulsive choice of risk-taking in AUD.	Alcohol Use Disorder	DNA methylation	Epigenome
469	32243864	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylationEPIC850 BeadChip	Illumina Infinium HumanMethylationEPIC850 BeadChip	Of the 774,516 CpG sites tested for differential DNAm between WS-affected case subjects and control subjects, we identified 229 statistically significant changes in DNAm across the genome at an FDR adjusted p value < 0.05 and |忖汕| ≡ 0.10. More than 81× of these sites showed hypomethylation in WS-affected case subjects compared to control subjects and the remaining 19× displayed hypermethylation in WS.	Intellectual Disability	DNA methylation	Epigenome
470	32398718	9606	Brain	Others	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip//EWAS	Illumina Infinium HumanMethylationEPIC BeadChip//EWAS	table1 Association of DNA methylation with AUD status across multiple cohorts.	Alcohol Use Disorder	DNA methylation	Epigenome
471	32493461	9606	Brain	Others	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	The present study provides evidence that the hypermethylation of theOPRM1promoter is in response to opioid use and that epigenetic differences inOPRM1and other sites are associated with a short-term use of therapeutic opioids.	Opioid Use Disorder	DNA methylation	Epigenome
472	32523041	9606	Brain(Prefrontal cortex)	DSM-IV	Case-control based	Illumina Human-MethylationEPIC BeadChip	Illumina Human-MethylationEPIC BeadChip	Variation in DNA methylation (DNAm) is associated with lifestyle factors such as smoking and body mass index (BMI) but there has been little research exploring its ability to identify individuals with Major Depressive Disorderr (MDD). Using penalised regression on genome-wide CpG methylation, we tested whether DNAm risk scores (MRS), trained on 1223 MDD cases and 1824 controls, could discriminate between cases (n = 363) and controls (n = 1417) in an independent sample, comparing their predictive accuracy to polygenic risk scores (PRS).	Major Depressive Disorder	DNA methylation	Epigenome
473	32523041	9606	Brain(Hippocampus)	DSM-IV	Case-control based	Illumina Human-MethylationEPIC BeadChip	Illumina Human-MethylationEPIC BeadChip	Variation in DNA methylation (DNAm) is associated with lifestyle factors such as smoking and body mass index (BMI) but there has been little research exploring its ability to identify individuals with Major Depressive Disorderr (MDD). Using penalised regression on genome-wide CpG methylation, we tested whether DNAm risk scores (MRS), trained on 1223 MDD cases and 1824 controls, could discriminate between cases (n = 363) and controls (n = 1417) in an independent sample, comparing their predictive accuracy to polygenic risk scores (PRS).	Major Depressive Disorder	DNA methylation	Epigenome
474	32523041	9606	Brain(Nucleus accumbens)	DSM-IV	Case-control based	Illumina Human-MethylationEPIC BeadChip	Illumina Human-MethylationEPIC BeadChip	Variation in DNA methylation (DNAm) is associated with lifestyle factors such as smoking and body mass index (BMI) but there has been little research exploring its ability to identify individuals with Major Depressive Disorderr (MDD). Using penalised regression on genome-wide CpG methylation, we tested whether DNAm risk scores (MRS), trained on 1223 MDD cases and 1824 controls, could discriminate between cases (n = 363) and controls (n = 1417) in an independent sample, comparing their predictive accuracy to polygenic risk scores (PRS).	Major Depressive Disorder	DNA methylation	Epigenome
475	32523041	9606	Brain(Pituitary)	DSM-IV	Case-control based	Illumina Human-MethylationEPIC BeadChip	Illumina Human-MethylationEPIC BeadChip	Variation in DNA methylation (DNAm) is associated with lifestyle factors such as smoking and body mass index (BMI) but there has been little research exploring its ability to identify individuals with Major Depressive Disorderr (MDD). Using penalised regression on genome-wide CpG methylation, we tested whether DNAm risk scores (MRS), trained on 1223 MDD cases and 1824 controls, could discriminate between cases (n = 363) and controls (n = 1417) in an independent sample, comparing their predictive accuracy to polygenic risk scores (PRS).	Major Depressive Disorder	DNA methylation	Epigenome
476	32523041	9606	Brain(Medial prefrontal cortex)	DSM-IV	Case-control based	Illumina Human-MethylationEPIC BeadChip	Illumina Human-MethylationEPIC BeadChip	Variation in DNA methylation (DNAm) is associated with lifestyle factors such as smoking and body mass index (BMI) but there has been little research exploring its ability to identify individuals with Major Depressive Disorderr (MDD). Using penalised regression on genome-wide CpG methylation, we tested whether DNAm risk scores (MRS), trained on 1223 MDD cases and 1824 controls, could discriminate between cases (n = 363) and controls (n = 1417) in an independent sample, comparing their predictive accuracy to polygenic risk scores (PRS).	Major Depressive Disorder	DNA methylation	Epigenome
477	32523041	9606	Brain(Olfactory bulbs)	DSM-IV	Case-control based	Illumina Human-MethylationEPIC BeadChip	Illumina Human-MethylationEPIC BeadChip	Variation in DNA methylation (DNAm) is associated with lifestyle factors such as smoking and body mass index (BMI) but there has been little research exploring its ability to identify individuals with Major Depressive Disorderr (MDD). Using penalised regression on genome-wide CpG methylation, we tested whether DNAm risk scores (MRS), trained on 1223 MDD cases and 1824 controls, could discriminate between cases (n = 363) and controls (n = 1417) in an independent sample, comparing their predictive accuracy to polygenic risk scores (PRS).	Major Depressive Disorder	DNA methylation	Epigenome
478	32650186	9606	Brain	CAM-ICU//DRS-R-98//DOSS	Case-control based	Illumina HumanMethylation450 BeadChip//Illumina Infinium HumanMethylationEPIC BeadChip	Illumina HumanMethylation450 BeadChip//Illumina Infinium HumanMethylationEPIC BeadChip	Furthermore, DNAm of neurotrophic genes were more positively correlated with age in Delirium cases than in non-Delirium controls.	Delirium	DNA methylation	Epigenome
479	32727556	9606	Brain(Prefrontal cortex)	ICD-10	Case-control based	Illumina Infinium Human Methylation450//Illumina Infinium MethylationEPIC 850K BeadChip	Illumina Infinium Human Methylation450//Illumina Infinium MethylationEPIC 850K BeadChip	In this pilot study, we did not only aim to find novel targets for ECT response prediction but also to get a deeper insight into its possible mechanism of action. Longitudinal DNA methylation analysis of peripheral blood mononuclear cells isolated from a cohort of treatment-resistant MDD patients (n = 12; time points: before and after 1st and last ECT, respectively) using a TruSeq-Methyl Capture EPIC Kit for library preparation.	Major Depressive Disorder	DNA methylation	Epigenome
480	32733030	9606	Brain(Prefrontal cortex)	DSM-III-R	Case-control based	Illumina HumanMethylation450 Beadchip//Illumina HumanOmniExpress//Affymetrix GeneChip 6.0	Illumina HumanMethylation450 Beadchip//Illumina HumanOmniExpress//Affymetrix GeneChip 6.0	We performed a brain epigenome-wide association study (EWAS) of late-life MDD in 608 participants from the Religious Order Study and the Rush Memory and Aging Project (ROS/MAP) using DNA methylation profiles of the dorsal lateral prefrontal cortex generated using the Illumina HumanMethylation450 Beadchip array. We also conducted an EWAS of MDD in each sex separately.	Major Depressive Disorder	DNA methylation	Epigenome
481	32799817	9606	Blood	DSM-ｍ	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	As such, we set the criteria for significance to a nominal p < 0.05 and |Δβ| > 5× to identify sites likely to be true associations while remaining cognizant of the increased risk of false positives. At this threshold, 188 CpG sites were associated with ADHD, and 82 CpGs were associated with OCD (Supplementary Table 1). Seven sites were associated with both ADHD and OCD and mapped to the following genes: DNAJC15 (2 CpGs), C13orf39, DLGAP2, and PRDM9; two CpGs were intergenic.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
482	32799817	9606	Blood	DSM-ｍ	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	As such, we set the criteria for significance to a nominalp< 0.05 and |忖汕| > 5× to identify sites likely to be true associations while remaining cognizant of the increased risk of false positives. At this threshold, 188 CpG sites were associated with ADHD, and 82 CpGs were associated with OCD (Supplementary Table1). Seven sites were associated with both ADHD and OCD and mapped to the following genes:DNAJC15(2 CpGs),C13orf39,DLGAP2, andPRDM9; two CpGs were intergenic.	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
483	32817534	9606	Brain	DSM-IV	Case-control based	Illumina HumanMethylation450 BeadChip//Illumina HumanMethylationEPIC BeadChip	Illumina HumanMethylation450 BeadChip//Illumina HumanMethylationEPIC BeadChip	The present study demonstrates thatNTRK2is epigenetically linked to memory functions in nontraumatized subjects and to PTSD risk and symptoms in traumatized populations.	Posttraumatic Stress Disorder	DNA methylation	Epigenome
484	32920561	9606	Brain	DSM-IV//Y-BOCS	Case-control based	Bisulfite Sequencing	Bisulfite Sequencing	Relative OXTR hypermethylation was observed in OCD patients compared to healthy controls.	Obsessive Compulsive Disorder	DNA methylation	Epigenome
485	32976583	9606	Brain	PCL-M//ACE//CES	Case-control based	PyroSequencing	PyroSequencing	Differentially methylated sites that were highly associated with PTSD diagnosis were found in three of seven candidate genes: BDNF, NR3C1, and MAN2C1.	Posttraumatic Stress Disorder	DNA methylation	Epigenome
486	33184255	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip//Meta-analysis	Illumina Infinium HumanMethylation450 BeadChip//Meta-analysis	Nine CpG sites showed genome-wide significance (p<1℅10-7, TableTable2).2).	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
487	33184255	9606	Blood	Others	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	Nine CpG sites showed genome-wide significance (p<1℅10-7, TableTable2).2).	Attention-Deficit/Hyperactivity Disorder	DNA methylation	Epigenome
488	33208194	9606	Brain	DSM-IV	Case-control based	Illumina HumanMethylation450 BeadChip//EWAS	Illumina HumanMethylation450 BeadChip//EWAS	The EWAS identified 61 differentially methylated CpGs (58 hypo- and 3 hypermethylated) in PD (Bonferroni adjustedP<1.33×10-7).	Panic Disorder	DNA methylation	Epigenome
489	33235198	9606	Brain	Others	Case-control based	Meta-analysis//Illumina HumanMethylation450 BeadChip	Meta-analysis//Illumina HumanMethylation450 BeadChip	Four CpG sites within the aryl-hydrocarbon receptor repressor (AHRR)associate with PTSD after adjustment for multiple comparisons, with lower DNA methylation in PTSD cases relative to controls.	Posttraumatic Stress Disorder	DNA methylation	Epigenome
490	33279932	9606	Brain	DSM-IV	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	The observed DNA methylation aberrations in schizophrenia patients could potentially provide a valuable resource for identifying diagnostic biomarkers and developing novel therapeutic targets to benefit schizophrenia patients.	Schizophrenia	DNA methylation	Epigenome
491	33340152	9606	Brain	Others	Case-control based	Bisulfite Pyrosequencing	Bisulfite Pyrosequencing	Peripheral blood α-synuclein intron 1 was hypomethylated in idiopathic rapid eye movement sleep behavior disorder patients.	Rapid Eye Movement Sleep Behavior Disorder	DNA methylation	Epigenome
492	33398089	9606	Brain	DSM-IV	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	The observed DNA methylation aberrations in schizophrenia patients could potentially provide a valuable resource for identifying diagnostic biomarkers and developing novel therapeutic targets to benefit schizophrenia patients.	Schizophrenia	DNA methylation	Epigenome
493	33414392	9606	Brain	DSM-IV//SCID II//DIB-R//MSI-BPD//CTQ-SF	Case-control based	Illumina Infinium HumanMethylation450 Beadchip	Illumina Infinium HumanMethylation450 Beadchip	Differentially methylated CpG sites were observed in several genes and intragenic regions in the X chromosome (PQBP1,ZNF41,RPL10, cg07810091 and cg24395855) and in chromosome 6 (TAP2). BPD patients showed significantly lower methylation levels in these CpG sites than healthy controls.	Borderline Personality Disorder	DNA methylation	Epigenome
494	33491855	9606	Brain	DSM-ｍ//SADQ//FTND	Case-control based	RT-PCR//EZ DNA Methylation-Gold Kit	RT-PCR//EZ DNA Methylation-Gold Kit	At baseline, there was a significantly higher gene-specific DNA methylation (ALDH2: p < .001 and MTHFR: p = .001) and a significant lower global methylation (LINE-1: p = .014) in AUD as compared to controls.	Alcohol Use Disorder	DNA methylation	Epigenome
495	33542190	9606	Brain	SCID	Case-control based	Illumina HumanMethylationEPIC BeadChip	Illumina HumanMethylationEPIC BeadChip	Investigating the DNAm data from all participants using DMRcate, eight differentially methylated CpG sites were identified which had a DNAm difference >5× and an FDR-correctedp-value <0.05 with respect to SAD (see Supplementary TableS2).	Social Anxiety Disorder	DNA methylation	Epigenome
496	33551813	10116	Brain	Others	Case-control based	Pyrosequencing	Pyrosequencing	The average GABRD methylation levels were significantly reduced in heroin self-administration group as compared to those in the yoked-saline group [F(2,26)= 5.91,p= 0.008;Figure 2A].	Heroin Addiction	DNA methylation	Epigenome
497	33875800	9606	Brain	Others	Case-control based	RRBS//qPCR//Affymetrix	RRBS//qPCR//Affymetrix	In this study, we performed promoter-wide DNA methylation analysis of neuronal and nonneuronal nuclei in the prefrontal cortex (PFC) of patients with BD. We performed promoter-wide DNA methylation analysis on NeuN-sorted neuronal (NeuN+) and nonneuronal (NeuN-) nuclear fractions derived from the PFC of patients with BD (N=34) and controls (N=35). We then identified DMRs between BD patients and controls.	Bipolar Disorder	DNA methylation	Epigenome
498	33909990	9606	Blood	Formal cognitive-behavioral assessments	Case-control based	WES//Gene Panel Sequencing//DNAm Microarray	WES//Gene Panel Sequencing//DNAm Microarray	Because FLHS is known to be associated with a unique set of DNA methylation (DNAm) changes in blood, a DNAm signature, we investigated whether there was a distinct signature associated with our affected individuals. We identified a subset of 77 differentially methylated CpG sites shared by the FLHS and proximal SRCAP DNAm signatures.	Neurodevelopmental Disorders	DNA methylation	Epigenome
499	33922358	9606	Brain	QEWPR-5//EAT-26	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	Differentially methylated sites in bulimia nervosa and binge-eating disorder	Eating Disorder	DNA methylation	Epigenome
500	33942629	9606	Brain	DSM-IV	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	The main objective of this study was to compare the DDR1 5-mC levels between patients with BD and healthy controls (HCs) in different data sets. A second objective was to test whether DDR1 5-mC levels alter total DDR1 and DDR1 isoform expression in the human brains of BD patients and HCs. Finally, we evaluated the comethylation of DDR1 with a selected set of myelin genes in the adult human brain to support that DDR1 is involved in myelination.	Bipolar Disorder	DNA methylation	Epigenome
501	33964519	9606	Brain	CAPS-CA//CRIES-13	Case-control based	Illumina Genomic Screening Array//Illumina HiSeq2000//RT-PCT	Illumina Genomic Screening Array//Illumina HiSeq2000//RT-PCT	Methylationdifferences on nine genes were replicated, including genes related toglucocorticoidfunctioning.	Posttraumatic Stress Disorder	DNA methylation	Epigenome
502	34192631	9606	Brain	CAM-ICU//DOSS//DRS-R-98	Case-control based	Pyrosequencing	Pyrosequencing	Negative correlations between age and DNAm with nominal significance were observed in 5 additionalCpG sitesin Delirium cases and only 4 CpG sites in non-Delirium controls (Table2).	Delirium	DNA methylation	Epigenome
503	34192631	9606	Brain	CAM-ICU//DOSS//DRS-R-98	Case-control based	Pyrosequencing	Pyrosequencing	In the blood samples, we found that 4 CpG showed significant negative correlation between their age and DNAm after correction for multiple testing	Delirium	DNA methylation	Epigenome
504	34269138	9606	Blood	DSM-IV	Case-control based	Illumina HumanMethylationEPIC850 BeadChip	Illumina HumanMethylationEPIC850 BeadChip	Here, we aimed to replicate findings of increased OXTR methylation as a predictor of disease and worse treatment response in an independent sample that received treatment within the public health care system. In addition, we aimed to extend previous findings by examining associations between OXTR hypermethylation, environmental stressors, OCD diagnosis, and treatment response. Methylation levels at two CpGs within OXTR exon III were compared between n = 181 OCD patients and n = 199 healthy controls using linear regression analysis. In a subsample of OCD patients (n = 98) with documented treatment data, we examined associations between methylation and treatment response to CBT. Childhood adversity and stressful life events were assessed using Childhood Trauma Questionnaire and Life Experience Survey, respectively. OCD patients exhibited significant hypermethylation at CpG site cg04523291 compared to controls, and increased methylation was associated with impaired treatment response.	Obsessive Compulsive Disorder	DNA methylation	Epigenome
505	34421516	9606	Brain	SCID//DSM-IV	Case-control based	Illumina Infinium HumanMethylationEPIC850 BeadChip	Illumina Infinium HumanMethylationEPIC850 BeadChip	The intronic single nucleotide polymorphism (SNP) rs10994336 within the ANK3 has emerged as one of the most replicated risk variants for bipolar disorder (BD) in genome-wide association studies. Our study suggests that BD-related genetic variant rs10994336 in ANK3 impacts executive functions by modulating ANK3 methylation, supporting the theory that methylation acts as a mediator between genotype and phenotype.	Bipolar Disorder	DNA methylation	Epigenome
506	34475392	9606	Brain	DSM-IV	Case-control based	Illumina HiSeq X Ten Sequencer	Illumina HiSeq X Ten Sequencer	DNA methylation (DNAm) is an epigenetic regulator of gene expression and a hallmark of gene-environment interaction. Using whole-genome bisulfite sequencing, we have surveyed DNAm in 344 samples of human postmortem brain tissue from neurotypical subjects and individuals with schizophrenia. We identify genetic influence on local methylation levels throughout the genome, both at CpG sites and CpH sites, with 86× of SNPs and 55× of CpGs being part of methylation quantitative trait loci (meQTLs).	Schizophrenia	DNA methylation	Epigenome
507	34475392	9606	Blood(Monocytes)	DSM-IV	Case-control based	Illumina HiSeq X Ten Sequencer	Illumina HiSeq X Ten Sequencer	DNA methylation (DNAm) is an epigenetic regulator of gene expression and a hallmark of gene-environment interaction. Using whole-genome bisulfite sequencing, we have surveyed DNAm in 344 samples of human postmortem brain tissue from neurotypical subjects and individuals with schizophrenia. We identify genetic influence on local methylation levels throughout the genome, both at CpG sites and CpH sites, with 86× of SNPs and 55× of CpGs being part of methylation quantitative trait loci (meQTLs).	Schizophrenia	DNA methylation	Epigenome
508	34475392	9606	blood	DSM-IV	Case-control based	Illumina HiSeq X Ten Sequencer	Illumina HiSeq X Ten Sequencer	DNA methylation (DNAm) is an epigenetic regulator of gene expression and a hallmark of gene-environment interaction. Using whole-genome bisulfite sequencing, we have surveyed DNAm in 344 samples of human postmortem brain tissue from neurotypical subjects and individuals with schizophrenia. We identify genetic influence on local methylation levels throughout the genome, both at CpG sites and CpH sites, with 86× of SNPs and 55× of CpGs being part of methylation quantitative trait loci (meQTLs).	Schizophrenia	DNA methylation	Epigenome
509	34475392	9606	Blood	DSM-IV	Case-control based	Illumina HiSeq X Ten Sequencer	Illumina HiSeq X Ten Sequencer	DNA methylation (DNAm) is an epigenetic regulator of gene expression and a hallmark of gene-environment interaction. Using whole-genome bisulfite sequencing, we have surveyed DNAm in 344 samples of human postmortem brain tissue from neurotypical subjects and individuals with schizophrenia. We identify genetic influence on local methylation levels throughout the genome, both at CpG sites and CpH sites, with 86× of SNPs and 55× of CpGs being part of methylation quantitative trait loci (meQTLs).	Schizophrenia	DNA methylation	Epigenome
510	34475392	9606	Blood//Brain	DSM-IV	Case-control based	Illumina HiSeq X Ten Sequencer	Illumina HiSeq X Ten Sequencer	DNA methylation (DNAm) is an epigenetic regulator of gene expression and a hallmark of gene-environment interaction. Using whole-genome bisulfite sequencing, we have surveyed DNAm in 344 samples of human postmortem brain tissue from neurotypical subjects and individuals with schizophrenia. We identify genetic influence on local methylation levels throughout the genome, both at CpG sites and CpH sites, with 86× of SNPs and 55× of CpGs being part of methylation quantitative trait loci (meQTLs).	Schizophrenia	DNA methylation	Epigenome
511	34475392	9606	Blood(Embryonic stem cells)	DSM-IV	Case-control based	Illumina HiSeq X Ten Sequencer	Illumina HiSeq X Ten Sequencer	DNA methylation (DNAm) is an epigenetic regulator of gene expression and a hallmark of gene-environment interaction. Using whole-genome bisulfite sequencing, we have surveyed DNAm in 344 samples of human postmortem brain tissue from neurotypical subjects and individuals with schizophrenia. We identify genetic influence on local methylation levels throughout the genome, both at CpG sites and CpH sites, with 86× of SNPs and 55× of CpGs being part of methylation quantitative trait loci (meQTLs).	Schizophrenia	DNA methylation	Epigenome
512	34475392	9606	Blood(T-cell)	DSM-IV	Case-control based	Illumina HiSeq X Ten Sequencer	Illumina HiSeq X Ten Sequencer	DNA methylation (DNAm) is an epigenetic regulator of gene expression and a hallmark of gene-environment interaction. Using whole-genome bisulfite sequencing, we have surveyed DNAm in 344 samples of human postmortem brain tissue from neurotypical subjects and individuals with schizophrenia. We identify genetic influence on local methylation levels throughout the genome, both at CpG sites and CpH sites, with 86× of SNPs and 55× of CpGs being part of methylation quantitative trait loci (meQTLs).	Schizophrenia	DNA methylation	Epigenome
513	34475392	9606	Blood(Leukocytes)	DSM-IV	Case-control based	Illumina HiSeq X Ten Sequencer	Illumina HiSeq X Ten Sequencer	DNA methylation (DNAm) is an epigenetic regulator of gene expression and a hallmark of gene-environment interaction. Using whole-genome bisulfite sequencing, we have surveyed DNAm in 344 samples of human postmortem brain tissue from neurotypical subjects and individuals with schizophrenia. We identify genetic influence on local methylation levels throughout the genome, both at CpG sites and CpH sites, with 86× of SNPs and 55× of CpGs being part of methylation quantitative trait loci (meQTLs).	Schizophrenia	DNA methylation	Epigenome
514	34475392	9606	Blood//Buccal swabs//Blood(Peripheral blood mononuclear cells)	DSM-IV	Case-control based	Illumina HiSeq X Ten Sequencer	Illumina HiSeq X Ten Sequencer	DNA methylation (DNAm) is an epigenetic regulator of gene expression and a hallmark of gene-environment interaction. Using whole-genome bisulfite sequencing, we have surveyed DNAm in 344 samples of human postmortem brain tissue from neurotypical subjects and individuals with schizophrenia. We identify genetic influence on local methylation levels throughout the genome, both at CpG sites and CpH sites, with 86× of SNPs and 55× of CpGs being part of methylation quantitative trait loci (meQTLs).	Schizophrenia	DNA methylation	Epigenome
515	34508068	9606	Brain(Hippocampus)	MINI	Case-control based	Illumina	Illumina	In the present work, we analyzed individuals with MDD (N = 201) and healthy controls (HC = 104), as part of the CAN-BIND-1 study. We used magnetic resonance imaging (MRI) to measure hippocampal volumes, evaluated gene expression with RNA sequencing, and assessed DNA methylation with the (Infinium MethylationEpic Beadchip), in order to investigate the association between hippocampal volume and both RNA expression and DNA methylation.	Major Depressive Disorder	DNA methylation	Epigenome
516	34508068	9606	Brain(Hippocampus)	MINI	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	In the present work, we analyzed individuals with MDD (N = 201) and healthy controls (HC = 104), as part of the CAN-BIND-1 study. We used magnetic resonance imaging (MRI) to measure hippocampal volumes, evaluated gene expression with RNA sequencing, and assessed DNA methylation with the (Infinium MethylationEpic Beadchip), in order to investigate the association between hippocampal volume and both RNA expression and DNA methylation.	Major Depressive Disorder	DNA methylation	Epigenome
517	34561420	9606	Brain	DSM-ｍ//K-SADS-PL	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	SLC25A24gene methylation and gray matter volume in females with and without conduct disorder: an exploratory epigenetic neuroimaging study	Conduct Disorder	DNA methylation	Epigenome
518	34582308	9606	Brain	DSM-ｍ//MAST//AUDIT	Case-control based	Bisulfite Pyrosequencing//PCR	Bisulfite Pyrosequencing//PCR	In the AUD group, compared with the control group, OPRM1 was hypermethylated(p < .01) but there was no significant difference in the methylation level of ALDH2 (p > .05).	Alcohol Use Disorder	DNA methylation	Epigenome
519	34627873	9606	Brain	Others	Case-control based	Meta-analysis	Meta-analysis	Table 1provides an overview of alcohol-inducedDNA methylationresponses in brains and blood samples from human subjects and animal models.	Alcohol Use Disorder	DNA methylation	Epigenome
520	34627873	10116	Brain	Others	Case-control based	Meta-analysis	Meta-analysis	Table 1provides an overview of alcohol-inducedDNA methylationresponses in brains and blood samples from human subjects and animal models.	Alcohol Use Disorder	DNA methylation	Epigenome
521	34627873	10090	Brain	Others	Case-control based	Meta-analysis	Meta-analysis	Table 1provides an overview of alcohol-inducedDNA methylationresponses in brains and blood samples from human subjects and animal models.	Alcohol Use Disorder	DNA methylation	Epigenome
522	34680906	9606	Brain	DSM-V	Case-control based//Family based	Illumina HumanMethylationEPIC BeadChip	Illumina HumanMethylationEPIC BeadChip	None of the investigated CpG sites reached a genome wide significance, but we identified nine CpG sites with suggestive significance (p< 1 ℅ 105,Table 1) and seven DMRs (id芍k-correctedp< 0.5,Table 3), which may be associated with TSD.	Tic Disorder	DNA methylation	Epigenome
523	34690045	9606	Blood	Others	Case-control based	ATAC-seq//RNA-seq//ChIP-seq	ATAC-seq//RNA-seq//ChIP-seq	The well-studied neuronal marker gene MAP2 was enriched for ATAC-seq signal at 12-24 h and H3K27ac signal at 48-72 h, with detection of MAP2 mRNA at 72 h.	Neurodevelopmental Disorders	Histone modification	Epigenome
524	34775485	9606	Brain	DSM-IV	Case-control based	Illumina HumanMethylationEPIC Beadchip	Illumina HumanMethylationEPIC Beadchip	Several novel CpG-sites and regions implicated in AUD were identified, providing a first basis to explore epigenetic correlates of AUD.	Alcohol Use Disorder	DNA methylation	Epigenome
525	34775485	9606	Brain	DSM-IV	Case-control based	Illumina EPIC BeadChip//Illumina HiScan Array	Illumina EPIC BeadChip//Illumina HiScan Array	This study aims to identify these mechanisms by examining differential DNA-methylation between cases with severe AUD (n = 53) and controls (n = 58) using a brain-region-specific approach, in which sample sizes ranged between 46 and 94. Samples of the anterior cingulate cortex (ACC), Brodmann Area 9 (BA9), caudate nucleus (CN), ventral striatum (VS), and putamen (PUT) were investigated. DNA-methylation levels were determined using the Illumina HumanMethylationEPIC Beadchip. Epigenome-wide association analyses were carried out to identify differentially methylated CpG-sites and regions between cases and controls in each brain region.	Alcohol Use Disorder	DNA methylation	Epigenome
526	34775485	9606	Brain	DSM-IV	Case-control based	Illumina HumanMethylationEPIC Beadchip//Pyrosequencing//TaqMan Assay	Illumina HumanMethylationEPIC Beadchip//Pyrosequencing//TaqMan Assay	Several novel CpG-sites and regions implicated in AUD were identified, providing a first basis to explore epigenetic correlates of AUD.	Alcohol Use Disorder	DNA methylation	Epigenome
527	34791764	9606	Brain	YAPA	Case-control based	MBD-seq//MWAS	MBD-seq//MWAS	As part of the most comprehensive methylation study of AUD to date, this work involved the first cell-type-specific methylation study of AUD conducted in blood, identifying and replicating a finding in DLGAP1 that may be a blood-based biomarker of AUD.	Alcohol Use Disorder	DNA methylation	Epigenome
528	34799556	9606	Brain	DTS//DSM-ｍ	Case-control based	Illumina EPIC BeadChip//EpiTYPER	Illumina EPIC BeadChip//EpiTYPER	TableTable44presents selected findings from the top twenty DMPs that were associated with PTSD before correction for multiple comparisons (p<0.05)	Posttraumatic Stress Disorder	DNA methylation	Epigenome
529	34857913	9606	Brain	SCID-IV//DSM-ｍ//DSM-IV	Case-control based	Illumina HumanMethylationEPIC BeadChip	Illumina HumanMethylationEPIC BeadChip	Results showed 2504 CpGs significantly associated with alcohol consumption (Bonferronipvalue < 6.8℅108) with the five leading probes located inSLC7A11(p=7.75℅10108), JDP2(p=1.44℅1056), GAS5(p=2.71℅1047), TRA2B(p=3.54℅1042), andSLC43A1(p=1.18℅1040).	Alcohol Use Disorder	DNA methylation	Epigenome
530	34857913	9606	Blood	DSM-IV-TR	Case-control based	Illumina HumanMethylationEPIC BeadChip	Illumina HumanMethylationEPIC BeadChip	Here we performed the largest single-cohort epigenome-wide association study (EWAS) of alcohol consumption to date (N = 8161) and cross-validated findings in AUD populations with relevant endophenotypes, as well as alcohol-related animal models. Results showed 2504 CpGs significantly associated with alcohol consumption (Bonferroni p value < 6.8 ℅ 10-8) with the five leading probes located in SLC7A11 (p = 7.75 ℅ 10-108), JDP2 (p = 1.44 ℅ 10-56), GAS5 (p = 2.71 ℅ 10-47), TRA2B (p = 3.54 ℅ 10-42), and SLC43A1 (p = 1.18 ℅ 10-40).	Alcohol Use Disorder	DNA methylation	Epigenome
531	34887385	9606	Brain	Confusion Assessment Method for the Intensive Care Unit (CAM-ICU)	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip//Pyrosequencing	Illumina Infinium HumanMethylationEPIC BeadChip//Pyrosequencing	Neurosurgery significantly altered DNAm levels at 17 out of 24 CpG sites on theTNFgene, 8 out of 14 CpG sites on theIL1Bgene, and 4 out of 14 CpG sites on theIL6gene.	Delirium	DNA methylation	Epigenome
532	34887385	9606	Brain	Confusion Assessment Method for the Intensive Care Unit (CAM-ICU)	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip//Pyrosequencing//PCR	Illumina Infinium HumanMethylationEPIC BeadChip//Pyrosequencing//PCR	Neurosurgery significantly altered DNAm levels at 17 out of 24 CpG sites on theTNFgene, 8 out of 14 CpG sites on theIL1Bgene, and 4 out of 14 CpG sites on theIL6gene.	Delirium	DNA methylation	Epigenome
533	34916236	9606	Brain	Liebowitz Social Anxiety Scale	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	DNA methylation at 1 CpG site located in intron 2 of theNR3C1gene (specifically cg25708981) was associated with the interaction of social anxiety disorder and early-life adversity (pFDR= 0.037).	Social Anxiety Disorder	DNA methylation	Epigenome
534	35013117	9606	Brain	DSM-IV-TR	Case-control based	Illumina HumanMethylationEPIC850 BeadChip	Illumina HumanMethylationEPIC850 BeadChip	Table 2 Identification of novel epigenetic loci associated to AN and results of the exploratory analysis in the validation cohort.	Anorexia Nervosa	DNA methylation	Epigenome
535	35057575	9606	Brain	Others	Case-control based	Illumina HumanMethylationEPIC Beadchip	Illumina HumanMethylationEPIC Beadchip	The blood-meQTLs analysis showed seven SNPs associated with DNA methylation levels of five CpG sites (Table 3).	Eating Disorder	DNA methylation	Epigenome
536	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 188 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
537	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 224 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
538	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 202 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
539	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 153 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
540	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 279 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
541	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 196 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
542	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 294 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
543	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 311 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
544	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 260 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
545	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 332 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
546	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 131 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
547	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 374 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
548	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 136 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
549	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 252 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
550	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 177 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
551	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 282 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
552	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 300 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
553	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 292 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
554	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 353 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
555	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 201 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
556	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 162 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
557	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 140 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
558	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 135 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
559	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 152 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
560	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 225 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
561	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 238 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
562	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 181 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
563	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 213 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
564	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 144 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
565	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 247 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
566	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 331 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
567	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 130 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
568	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 192 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
569	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 280 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
570	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 348 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
571	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 326 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
572	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 303 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
573	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 248 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
574	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 355 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
575	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 145 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
576	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 160 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
577	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 163 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
578	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 312 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
579	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 173 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
580	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 339 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
581	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 169 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
582	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 364 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
583	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 194 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
584	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 250 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
585	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 373 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
586	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 296 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
587	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 297 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
588	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 212 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
589	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 358 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
590	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 197 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
591	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 371 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
592	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 305 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
593	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 178 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
594	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 363 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
595	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 369 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
596	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 306 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
597	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 182 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
598	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 323 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
599	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 290 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
600	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 208 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
601	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 309 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
602	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 218 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
603	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 343 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
604	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 315 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
605	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 269 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
606	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 185 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
607	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 166 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
608	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 150 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
609	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 302 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
610	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 356 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
611	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 357 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
612	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 328 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
613	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 313 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
614	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 174 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
615	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 141 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
616	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 360 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
617	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 222 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
618	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 262 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
619	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 149 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
620	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 239 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
621	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 138 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
622	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 205 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
623	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 164 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
624	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 270 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
625	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 271 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
626	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 367 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
627	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 335 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
628	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 365 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
629	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 263 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
630	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 291 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
631	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 264 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
632	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 214 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
633	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 265 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
634	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 168 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
635	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 246 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
636	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 232 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
637	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 257 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
638	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 191 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
639	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 195 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
640	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 235 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
641	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 179 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
642	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 147 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
643	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 376 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
644	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 351 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
645	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 299 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
646	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 193 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
647	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 187 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
648	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 171 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
649	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 321 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
650	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 368 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
651	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 277 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
652	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 342 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
653	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 276 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
654	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 137 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
655	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 142 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
656	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 249 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
657	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 158 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
658	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 198 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
659	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 242 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
660	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 146 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
661	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 244 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
662	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 236 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
663	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 220 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
664	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 228 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
665	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 338 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
666	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 211 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
667	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 330 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
668	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 327 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
669	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 346 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
670	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 210 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
671	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 287 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
672	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 227 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
673	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 361 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
674	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 237 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
675	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 354 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
676	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 204 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
677	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 233 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
678	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 175 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
679	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 186 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
680	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 316 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
681	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 340 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
682	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 286 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
683	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 148 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
684	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 352 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
685	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 129 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
686	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 337 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
687	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 289 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
688	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 266 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
689	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 295 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
690	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 217 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
691	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 314 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
692	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 293 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
693	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 272 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
694	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 267 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
695	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 329 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
696	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 134 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
697	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 234 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
698	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 167 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
699	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 216 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
700	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 207 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
701	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 165 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
702	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 308 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
703	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 245 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
704	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 347 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
705	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 281 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
706	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 349 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
707	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 341 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
708	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 259 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
709	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 256 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
710	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 284 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
711	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 159 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
712	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 298 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
713	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 203 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
714	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 317 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
715	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 132 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
716	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 320 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
717	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 366 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
718	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 155 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
719	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 268 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
720	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 176 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
721	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 319 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
722	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 258 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
723	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 334 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
724	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 157 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
725	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 336 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
726	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 304 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
727	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 139 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
728	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 243 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
729	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 359 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
730	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 190 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
731	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 199 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
732	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 183 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
733	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 184 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
734	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 310 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
735	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 254 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
736	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 151 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
737	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 345 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
738	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 322 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
739	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 307 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
740	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 255 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
741	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 253 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
742	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 143 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
743	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 333 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
744	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 370 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
745	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 200 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
746	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 275 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
747	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 261 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
748	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 318 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
749	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 375 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
750	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 350 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
751	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 154 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
752	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 273 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
753	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 274 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
754	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 230 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
755	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 278 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
756	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 231 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
757	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 241 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
758	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 170 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
759	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 221 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
760	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 325 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
761	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 172 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
762	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 324 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
763	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 209 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
764	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 283 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
765	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 288 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
766	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 344 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
767	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 206 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
768	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 189 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
769	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 133 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
770	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 180 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
771	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 161 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
772	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 219 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
773	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 223 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
774	35089926	9606	Brain	DSM-ｍ//K-SADS-PL//Wechsler Intelligence Test	Case-control based	Illumina HiSeq2000//RT-PCR	Illumina HiSeq2000//RT-PCR	Descriptively, 237 tags were associated with group status at uncorrectedP≒ 10E-3 (S1 Table). Of these, 108 tags were less methylated (log2FC > 0) in cases whereas 372 tags showed an increased methylation.	Conduct Disorder	DNA methylation	Epigenome
775	35163737	9606	Blood	NA	Case-control based	Illumina Infinium HumanMethylation450 BeadChip	Illumina Infinium HumanMethylation450 BeadChip	We assessed genome-wide DNA methylation profiles in a cohort of 60 patients with clinical diagnosis for WDSTS or Kabuki and identified a unique highly sensitive and specific DNA methylation episignature as a molecular biomarker of WDSTS.	Intellectual Disability	DNA methylation	Epigenome
776	35177594	9606	Saliva	PCL-S	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	We performed one of the largest single-sample epigenome-wide association studies (EWAS) of PTSD to date. Our sample included 1135 male European-American U.S. veterans who participated in the National Health and Resilience in Veterans Study (NHRVS). DNA was collected from saliva samples and the Illumina HumanMethylation EPIC BeadChip was used for the methylation analysis. PTSD was assessed using the PTSD Checklist. An EWAS was conducted using linear regression adjusted for age, cell-type proportions, first 10 principal components, and smoking status. After Bonferroni correction, we identified six genome-wide significant (GWS) CpG sites associated with past-month PTSD and three CpGs with lifetime PTSD (prange = 10-10-10-8).	Posttraumatic Stress Disorder	DNA methylation	Epigenome
777	35283726	9606	Brain(Hippocampus)	DSM-IV	Case-control based	Illumina HumanMethylation450 BeadChip	Illumina HumanMethylation450 BeadChip	Methylation data from 533 samples were extracted from the Gene Expression Omnibus (GEO) database, of which, 324 individuals were diagnosed with MDD. Statistical difference of DNA Methylation between Promoter and Other body region (SIMPO) score for each gene was calculated based on the DNA methylation data. Based on SIMPO scores, we selected the top genes that showed a correlation with MDD in random resampling, then proposed a methylation-derived Depression Index (mDI) by combining the SIMPO of the selected genes to predict MDD.	Major Depressive Disorder	DNA methylation	Epigenome
778	35299244	9606	Blood	NA	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	Here, using Illumina MethylationEPIC arrays, we have longitudinally analysed the peripheral blood methylomes of cognitively healthy older adults (> 70 yr), some of whom went on to develop dementia while others stayed healthy. We have characterized 34 individuals at the pre-diagnosis stage and at a 4-year follow-up in the post-diagnosis stage (total n = 68). Our results show multiple DNA methylation alterations linked to dementia status, particularly at the level of differentially methylated regions. These loci are associated with several dementia-related genes, including PON1, AP2A2, MAGI2, POT1, ITGAX, PACSIN1, SLC2A8 and EIF4E.	Neurocognitive Disorders	DNA methylation	Epigenome
779	35361281	9606	Blood//Saliva	DSM-V	Case-control based	PCR//Pyrosequencing	PCR//Pyrosequencing	Higher levels of oxytocin receptor gene DNA methylation, inversely correlated with gene expression, were observed in the blood as well as saliva of OCD subjects when compared to controls. Moreover, Actinobacteria also resulted higher in OCD and directly correlated with oxytocin receptor gene epigenetic alterations. The same pattern of changes was present in the prefrontal cortex of socially-isolated rats, where also altered levels of fecal butyrate were observed at the beginning of the isolation procedure.	Obsessive Compulsive Disorder	DNA methylation	Epigenome
780	35477560	9606	Blood	DSM-IV	Case-control based	Illumina HumanMethylation450 BeadChip//Meta-analysis	Illumina HumanMethylation450 BeadChip//Meta-analysis	Two CpG-sites presented with p-values below 1 ℅ 10-05 in PD: cg09738429 (p = 6.40 ℅ 10-06, located in an intergenic shore region in next proximity of PYROXD1) and cg03341655 (p = 8.14 ℅ 10-06, located in the exonic region of GFOD2). The association of DNAm at cg03341655 and wLE could be replicated in the independent MDD case sample indicating a diagnosis independent effect. Genes mapping to the top hits were significantly upregulated in brain and top hits have been implicated in the metabolic system. Additionally, two significant DMRs were identified for PD only on chromosome 10 and 18, including CpG-sites which have been reported to be associated with anxiety and other psychiatric phenotypes.	Major Depressive Disorder	DNA methylation	Epigenome
781	35627945	9606	Blood	C-SSRS	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	This cross-sectional study comprised 112 subjects diagnosed with schizophrenia spectrum disorders, and were grouped according to the current suicidal ideation severity. DNA methylation across the genome was measured with the Infinium MethylationEPIC BeadChip. We utilized the dmpFinder and bumphunter functions within the Bioconductor minfi package to identify differentially methylated positions (DMPs) and differentially methylated regions (DMRs), respectively. Following quality control, we removed one sample from the analysis and reported the most significant DMPs and DMRs associated with suicidal ideation severity. All positions and regions identified in this analysis were only found to have suggestive levels of significance at the genome-wide level.	Schizophrenia	DNA methylation	Epigenome
782	35628578	9606	NA	DSM-IV	Case-control based	Illumina Infinium HumanMethylationEPIC BeadChip	Illumina Infinium HumanMethylationEPIC BeadChip	This cross-sectional study comprised 112 subjects diagnosed with schizophrenia spectrum disorders, and were grouped according to the current suicidal ideation severity. DNA methylation across the genome was measured with the Infinium MethylationEPIC BeadChip. We utilized the dmpFinder and bumphunter functions within the Bioconductor minfi package to identify differentially methylated positions (DMPs) and differentially methylated regions (DMRs), respectively. Following quality control, we removed one sample from the analysis and reported the most significant DMPs and DMRs associated with suicidal ideation severity. All positions and regions identified in this analysis were only found to have suggestive levels of significance at the genome-wide level.	Major Depressive Disorder	DNA methylation	Epigenome
783	35650177	9606	Blood	DSM-IV	Case-control based	Illumina HumanMethylationEPIC BeadChip	Illumina HumanMethylationEPIC BeadChip	Here, an epigenome-wide association study (EWAS) was performed in a sample of 76 OCD patients of European ancestry (37 women, age ㊣ SD: 33.51 ㊣ 10.92 years) and 76 sex- and age-matched healthy controls for the first time using the Illumina MethylationEPIC BeadChip. After quality control, nine epigenome-wide significant quantitative trait methylation sites (QTMs) and 21 suggestive hits were discerned in the final sample of 68 patients and 68 controls. The top hit (cg24159721) and four other significant QTMs (cg11894324, cg01070250, cg11330075, cg15174812) map to the region of the microRNA 12136 gene (MIR12136). Two additional significant CpG sites (cg05740793, cg20450977) are located in the flanking region of the MT-RNR2 (humanin) like 8 gene (MT-RNRL8), while two further QTMs (cg16267121, cg15890734) map to the regions of the MT-RNR2 (humanin) like 3 (MT-RNRL3) and MT-RNR2 (humanin) like 2 (MT-RNRL2) genes.	Obsessive Compulsive Disorder	DNA methylation	Epigenome
784	35703085	9606	Blood	DSM-V	Case-control based	Illumina Infinium HumanMethylation450 BeadChip//Illumina Infinium MethylationEPIC BeadChip	Illumina Infinium HumanMethylation450 BeadChip//Illumina Infinium MethylationEPIC BeadChip	We measured genome-wide DNA methylation in 145 women with active AN, 49 showing stable one-year remission of AN, and 64 with no ED. Probes and identified genes that overlapped between AN-active versus No Eating Disorder participants (NED) and AN-active versus AN-remitted comparisons at Q <.01	Anorexia Nervosa	DNA methylation	Epigenome
785	35752218	9606	Blood	DSM-IV	Case-control based	MethylTarget//PCR	MethylTarget//PCR	The mean methylation of all P11 CpG sites, as well as the methylation at 4 CpG sites (P11-2-169, P11-2-192, P11-2-202, P11-2-204), were significantly higher in patients with MDD than in healthy controls (FDR-corrected P < 0.05). The response to antidepressants was associated with the following interactions: the CTQ score and P11-3-185 site methylation (OR = 0.297, FDR-corrected P = 0.023), the CTQ physical neglect score and P11-2-117 site methylation (OR = 0.005, FDR-corrected P = 0.033), and the CTQ emotional abuse score and P11-3-185 site methylation (OR = 0.001, FDR-corrected P = 0.023).	Major Depressive Disorder	DNA methylation	Epigenome
